Clinical decision support systems for improving diagnostic accuracy and achieving precision medicine

C Castaneda, K Nalley, C Mannion… - Journal of clinical …, 2015 - Springer
As research laboratories and clinics collaborate to achieve precision medicine, both
communities are required to understand mandated electronic health/medical record …

Multiomic analysis of cytokines in immuno-oncology

V Jurisic - Expert review of proteomics, 2020 - Taylor & Francis
Introduction: Cytokines are a diverse group of peptides produced by different cell types
including cancer cells and various subpopulations of immune system cells. They exert their …

Genomic atlas of the human plasma proteome

BB Sun, JC Maranville, JE Peters, D Stacey, JR Staley… - Nature, 2018 - nature.com
Although plasma proteins have important roles in biological processes and are the direct
targets of many drugs, the genetic factors that control inter-individual variation in plasma …

The human O-GlcNAcome database and meta-analysis

E Wulff-Fuentes, RR Berendt, L Massman, L Danner… - Scientific data, 2021 - nature.com
Abstract Over the past 35 years,~ 1700 articles have characterized protein O-GlcNAcylation.
Found in almost all living organisms, this post-translational modification of serine and …

MaizeGDB 2018: the maize multi-genome genetics and genomics database

JL Portwood, MR Woodhouse, EK Cannon… - Nucleic acids …, 2019 - academic.oup.com
Since its 2015 update, MaizeGDB, the Maize Genetics and Genomics database, has
expanded to support the sequenced genomes of many maize inbred lines in addition to the …

Obesity-associated variants within FTO form long-range functional connections with IRX3

S Smemo, JJ Tena, KH Kim, ER Gamazon, NJ Sakabe… - Nature, 2014 - nature.com
Genome-wide association studies (GWAS) have reproducibly associated variants within
introns of FTO with increased risk for obesity and type 2 diabetes (T2D),,. Although the …

WormBase 2016: expanding to enable helminth genomic research

KL Howe, BJ Bolt, S Cain, J Chan, WJ Chen… - Nucleic acids …, 2016 - academic.oup.com
Abstract WormBase (www. wormbase. org) is a central repository for research data on the
biology, genetics and genomics of Caenorhabditis elegans and other nematodes. The …

[图书][B] Model organisms

RA Ankeny, S Leonelli - 2020 - cambridge.org
This Element presents a philosophical exploration of the concept of the'model organism'in
contemporary biology. Thinking about model organisms enables us to examine how living …

Nucleoporin TPR is an integral component of the TREX-2 mRNA export pathway

V Aksenova, A Smith, H Lee, P Bhat, C Esnault… - Nature …, 2020 - nature.com
Nuclear pore complexes (NPCs) are important for cellular functions beyond
nucleocytoplasmic trafficking, including genome organization and gene expression. This …

Araport: the Arabidopsis information portal

V Krishnakumar, MR Hanlon, S Contrino… - Nucleic acids …, 2015 - academic.oup.com
Abstract The Arabidopsis Information Portal (https://www. araport. org) is a new online
resource for plant biology research. It houses the Arabidopsis thaliana genome sequence …