A systematic review on the kappa opioid receptor and its ligands: New directions for the treatment of pain, anxiety, depression, and drug abuse

MIH Khan, BJ Sawyer, NS Akins, HV Le - European Journal of Medicinal …, 2022 - Elsevier
Kappa opioid receptor (KOR) is a member of the opioid receptor system, the G protein-
coupled receptors that are expressed throughout the peripheral and central nervous …

Historical perspectives and recent advances in small molecule ligands of selective/biased/multi-targeted μ/δ/κ opioid receptor (2019–2022)

Y He, Q Su, L Zhao, L Zhang, L Yu, J Shi - Bioorganic Chemistry, 2023 - Elsevier
The opioids have been used for more than a thousand years and are not only the most
widely prescribed drugs for moderate to severe pain and acute pain, but also the preferred …

Fimbristylis aestivalis Vahl: a potential source of cyclooxygenase-2 (COX-2) inhibitors

S Talukder, KS Ahmed, H Hossain, T Hasan… - …, 2022 - Springer
Abstract Cyclooxygenase-2 (COX-2) is an inducible enzyme that accelerates the
biosynthesis of PGs during inflammation and has emerged as an important therapeutic …

[HTML][HTML] Therapeutic Potential of Salvinorin A and Its Analogues in Various Neurological Disorders

J Cichon, R Liu, HV Le - Translational perioperative and pain …, 2022 - ncbi.nlm.nih.gov
While the hallucinogenic plant Salvia divinorum has been safely consumed by humans for
centuries for religious or recreational purposes without long-term side effects, its active …

Alleviation of cocaine withdrawal and pertinent interactions between salvinorin-based antagonists and kappa opioid receptor

NS Akins, MF Salahuddin, P Pandey… - ACS Chemical …, 2023 - ACS Publications
The kappa opioid receptor (KOR) is involved in the regulation of both the reward and mood
processes. Recent reports find that the use of drugs of abuse increases the production of …

Heteroaromatic salvinorin A analogue (P-3 l) elicits antinociceptive and anxiolytic-like effects

CVL Moreira, ALG Faria, DPB Silva, PC Ghedini… - Fitoterapia, 2023 - Elsevier
Previous studies have attributed the prominent analgesic, hallucinogenic, sedative, and
anxiolytic properties of Salvia divinorum to Salvinorin A. However, the overall …

[PDF][PDF] Research News, Publications, 2021, Volume 3

S Majumdar - 2021 - egrove.olemiss.edu
22. De La Cruz LK, Yang X, Menshikh A, Brewer M, Lu W, Wang M, Wang S, Ji X, Cachuela
A, Yang H, Gallo D, Tan C, Otterbein L, de Caestecker M, Wang B. Adapting decarbonylation …