Langya henipavirus outbreak

VP Chavda, V Apostolopoulos… - Expert Review of Anti …, 2023 - Taylor & Francis
2. Discussion To grasp the evolution of this outbreak, comprehensive monitoring and
surveillance are imperative, especially within China and its neighboring countries …

Structure and design of Langya virus glycoprotein antigens

Z Wang, M McCallum, L Yan… - Proceedings of the …, 2024 - National Acad Sciences
Langya virus (LayV) is a recently discovered henipavirus (HNV), isolated from febrile
patients in China. HNV entry into host cells is mediated by the attachment (G) and fusion (F) …

A comprehensive review of Langya virus and framework for future zoonotic disease control

DH Thien, HB Tran, NNP Uyen… - Reviews in Medical …, 2024 - Wiley Online Library
First reported in August 2022, the Langya virus (LayV) has emerged as a potential global
health threat in the post‐COVID‐19 era. Preliminary reports show that 35 patients near …

The cryo-EM structure of homotetrameric attachment glycoprotein from langya henipavirus

Y Guo, S Wu, W Li, H Yang, T Shi, B Ju, Z Zhang… - Nature …, 2024 - nature.com
Abstract Langya Henipavirus (LayV) infection is an emerging zoonotic disease that has
been causing respiratory symptoms in China since 2019. For virus entry, LayV's genome …

Prefusion stabilization of the Hendra and Langya virus F proteins

PO Byrne, EG Blade, BE Fisher, DR Ambrozak… - Journal of …, 2024 - Am Soc Microbiol
ABSTRACT Nipah virus (NiV) and Hendra virus (HeV) are pathogenic paramyxoviruses that
cause mild-to-severe disease in humans. As members of the Henipavirus genus, NiV and …

Universal paramyxovirus vaccine design by stabilizing regions involved in structural transformation of the fusion protein

JPM Langedijk, F Cox, NV Johnson… - Nature …, 2024 - nature.com
The Paramyxoviridae family encompasses medically significant RNA viruses, including
human respiroviruses 1 and 3 (RV1, RV3), and zoonotic pathogens like Nipah virus (NiV) …

[HTML][HTML] Development of a high-throughput platform for quantitation of histone modifications on a new QTOF instrument

E Zahn, Y Xie, X Liu, R Karki, RM Searfoss… - Molecular & Cellular …, 2024 - Elsevier
Histone post-translational modifications (PTMs) regulate gene expression patterns through
epigenetic mechanisms. The 5 histone proteins (H1, H2A, H2B, H3, and H4) are extensively …

Meeting Report of the 37th International Conference on Antiviral Research in Gold Coast, Australia, May 20–24, 2024, organized by the International Society for …

SR Welch, JP Bilello, K Carter, L Delang, L Dirr… - Antiviral Research, 2024 - Elsevier
Abstract The 37 th International Conference on Antiviral Research (ICAR) was held in Gold
Coast, Australia, May 20–24, 2024. ICAR 2024 featured over 75 presentations along with …

Structural insights into the Langya virus attachment glycoprotein

C Wang, M Li, Y Wang, Q Ding, S Fan, J Lan - Structure, 2024 - cell.com
Langya virus (LayV) was recently detected in patients with acute pneumonic diseases in
China. Genome alignment indicated that LayV is a type of zoonotic henipavirus (HNV) that …

[HTML][HTML] A Comparative Assessment of the Pathogenic Potential of Newly Discovered Henipaviruses

K Meier, J Olejnik, AJ Hume, E Mühlberger - Pathogens, 2024 - mdpi.com
Recent advances in high-throughput sequencing technologies have led to the discovery of a
plethora of previously unknown viruses in animal samples. Some of these newly detected …