Immunological memory to SARS‐CoV‐2 infection and COVID‐19 vaccines

A Sette, S Crotty - Immunological reviews, 2022 - Wiley Online Library
Immunological memory is the basis of protective immunity provided by vaccines and
previous infections. Immunological memory can develop from multiple branches of the …

Correlates of protection against SARS‐CoV‐2 infection and COVID‐19 disease

D Goldblatt, G Alter, S Crotty… - Immunological reviews, 2022 - Wiley Online Library
Antibodies against epitopes in S1 give the most accurate CoP against infection by the SARS‐
CoV‐2 coronavirus. Measurement of those antibodies by neutralization or binding assays …

The SARS-CoV-2 monoclonal antibody combination, AZD7442, is protective in nonhuman primates and has an extended half-life in humans

YM Loo, PM McTamney, RH Arends… - Science translational …, 2022 - science.org
Despite the success of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
vaccines, there remains a need for more prevention and treatment options for individuals …

The humoral response and antibodies against SARS-CoV-2 infection

H Qi, B Liu, X Wang, L Zhang - Nature Immunology, 2022 - nature.com
Two and a half years into the COVID-19 pandemic, we have gained many insights into the
human antibody response to the causative SARS-CoV-2 virus. In this Review, we …

SARS-CoV-2 infection rates of antibody-positive compared with antibody-negative health-care workers in England: a large, multicentre, prospective cohort study …

VJ Hall, S Foulkes, A Charlett, A Atti, EJM Monk… - The Lancet, 2021 - thelancet.com
Background Increased understanding of whether individuals who have recovered from
COVID-19 are protected from future SARS-CoV-2 infection is an urgent requirement. We …

[HTML][HTML] SARS-CoV-2 variants B. 1.351 and P. 1 escape from neutralizing antibodies

M Hoffmann, P Arora, R Groß, A Seidel, BF Hörnich… - Cell, 2021 - cell.com
The global spread of SARS-CoV-2/COVID-19 is devastating health systems and economies
worldwide. Recombinant or vaccine-induced neutralizing antibodies are used to combat the …

Evidence of escape of SARS-CoV-2 variant B. 1.351 from natural and vaccine-induced sera

D Zhou, W Dejnirattisai, P Supasa, C Liu, AJ Mentzer… - Cell, 2021 - cell.com
The race to produce vaccines against severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) began when the first sequence was published, and this forms the basis for …

Defining the risk of SARS-CoV-2 variants on immune protection

MM DeGrace, E Ghedin, MB Frieman, F Krammer… - Nature, 2022 - nature.com
The global emergence of many severe acute respiratory syndrome coronavirus 2 (SARS-
CoV-2) variants jeopardizes the protective antiviral immunity induced after infection or …

SARS-CoV-2 501Y. V2 escapes neutralization by South African COVID-19 donor plasma

CK Wibmer, F Ayres, T Hermanus, M Madzivhandila… - Nature medicine, 2021 - nature.com
Abstract SARS-CoV-2 501Y. V2 (B. 1.351), a novel lineage of coronavirus causing COVID-
19, contains substitutions in two immunodominant domains of the spike protein. Here, we …

[HTML][HTML] Adaptive immunity to SARS-CoV-2 and COVID-19

A Sette, S Crotty - Cell, 2021 - cell.com
The adaptive immune system is important for control of most viral infections. The three
fundamental components of the adaptive immune system are B cells (the source of …