Arachidonic acid modulates the cellular energetics of human pluripotent stem cells and protects the embryoid bodies from embryotoxicity effects in vitro

M Nihad, U Sen, D Chaudhury, UN Das, S Shenoy… - Reproductive …, 2023 - Elsevier
Arachidonic acid (AA), an ω-6 polyunsaturated fatty acid involved in signalling pathways that
drive cell fate decisions, has an enhancing role in the immunomodulatory effect on …

Luminescent 11-{Naphthalen-1-yl} dipyrido [3, 2-a: 2′, 3′-c] phenazine-Based Ru (II)/Ir (III)/Re (I) Complexes for HCT-116 Colorectal Cancer Stem Cell Therapy

U Das, S Shanavas, AH Nagendra, B Kar… - ACS Applied Bio …, 2023 - ACS Publications
Due to a number of unpleasant considerations, marketed drugs have steadily lost their
importance in the treatment of cancer. In order to find a viable cancer cell diagnostic agent …

Prevention of MEK-ERK-1/2 hyper-activation underlines the neuroprotective effect of Glycyrrhiza glabra L.(Yashtimadhu) against rotenone-induced cellular and …

G Karthikkeyan, R Pervaje, SK Pervaje… - Journal of …, 2021 - Elsevier
Ethnopharmacological relevance Yashtimadhu choorna (powder) is prepared from the dried
root of Glycyrrhiza glabra L., commonly known as licorice. The Indian Ayurvedic system …

Identification of Molecular Network Associated with Neuroprotective Effects of Yashtimadhu (Glycyrrhiza glabra L.) by Quantitative Proteomics of Rotenone-Induced …

G Karthikkeyan, MA Najar, R Pervaje, SK Pervaje… - Acs Omega, 2020 - ACS Publications
Parkinson's disease (PD) is a progressive neurodegenerative disorder, whose treatment
with modern therapeutics leads to a plethora of side effects with prolonged usage …

Novel pH responsive hesperidin nanoformulation exerts anticancer activity on lung adenocarcinoma cells by targeting Akt/mTOR and MEK/ERK pathways

SR Pavan, A Prabhu - Journal of Materials Research, 2024 - Springer
Zinc oxide nanoparticle based drug delivery enhances bioavailability of anticancer drug to
the tumor site. We developed novel biocompatible ZnO nanoparticles for the targeted …

[HTML][HTML] Efficacy of a filtered far-UVC handheld disinfection device in reducing the microbial bioburden of hospital surfaces

T Navarathna, C Jinadatha, BA Corona… - American Journal of …, 2023 - Elsevier
Background The filtered far-UV-C (FFUV) handheld disinfection device is a small portable
device that emits far UV-C at 222 nm. The objective of this study was to evaluate the device's …

Thorium promotes lung, liver and kidney damage in BALB/c mouse via alterations in antioxidant systems

D Chaudhury, U Sen, BK Sahoo, NN Bhat… - Chemico-Biological …, 2022 - Elsevier
Abstract Thorium (232 Th), long lived (14.05 billion years) most stable thorium isotope, is
thrice naturally abundant than uranium. 232 Th occurs as rocky deposits and black monazite …

Assessment of threshold dose of thoron inhalation and its biological effects by mimicking the radiation doses in monazite placer deposits corresponding to the normal …

D Chaudhury, U Sen, S Biswas, S Shenoy P… - Biological Trace Element …, 2023 - Springer
The dose contributed from thoron (220Rn) and its progeny has been neglected in the dose
assessment because of its short half-life (t1/2= 55.6 s) and generally low concentrations …

Iridium (III)–Cp*-(imidazo [4, 5-f][1, 10] phenanthrolin-2-yl) phenol analogues as hypoxia active, GSH-resistant cancer cytoselective and mitochondria-targeting cancer …

B Kar, S Shanavas, AH Nagendra, U Das, N Roy… - Dalton …, 2022 - pubs.rsc.org
Herein, we have introduced a series of iridium (III)–Cp*-(imidazo [4, 5-f][1, 10] phenanthrolin-
2-yl) phenol complexes via a convenient synthetic methodology, which act as hypoxia active …

Acid Degradable Zinc Oxide Nanoparticle Loaded Etoposide Nanoformulation for Targeting Lung Adenocarcinoma via Drug Metabolism and Crosstalk Between …

SR Pavan, A Prabhu - BioNanoScience, 2024 - Springer
Lung Cancer is a leading cause of death worldwide, and if diagnosed at later stages, it can
be lethal and incurable. Lung cancer is conventionally treated using chemotherapy. Among …