Nuclear mRNA decay: regulatory networks that control gene expression
Proper regulation of mRNA production in the nucleus is critical for the maintenance of
cellular homoeostasis during adaptation to internal and environmental cues. Over the past …
cellular homoeostasis during adaptation to internal and environmental cues. Over the past …
Inner nuclear membrane proteins Lem2 and Bqt4 interact with different lipid synthesis enzymes in fission yeast
Y Hirano, Y Kinugasa, Y Kubota… - The Journal of …, 2023 - academic.oup.com
The nuclear envelope (NE) is a double-membrane structure consisting of inner and outer
membranes that spatially separate the nucleus from the cytoplasm, and its function is critical …
membranes that spatially separate the nucleus from the cytoplasm, and its function is critical …
Ceramide synthase homolog Tlc4 maintains nuclear envelope integrity via its Golgi translocation
Maintaining the integrity of the nuclear envelope (NE) is essential for preventing genomic
DNA damage. Recent studies have shown that enzymes that catalyze lipid synthesis are …
DNA damage. Recent studies have shown that enzymes that catalyze lipid synthesis are …
[HTML][HTML] DEAD-box ATPase Dbp2 is the key enzyme in an mRNP assembly checkpoint at the 3'-end of genes and involved in the recycling of cleavage factors
E Aydin, S Schreiner, J Böhme, B Keil, J Weber… - Nature …, 2024 - nature.com
Abstract mRNA biogenesis in the eukaryotic nucleus is a highly complex process. The
numerous RNA processing steps are tightly coordinated to ensure that only fully processed …
numerous RNA processing steps are tightly coordinated to ensure that only fully processed …
[HTML][HTML] Organization and epigenomic control of RNA polymerase III-transcribed genes in plants
The genetic information linearly scripted in chromosomes is wrapped in a ribonucleoprotein
complex called chromatin. The adaptation of its compaction level and spatiotemporal …
complex called chromatin. The adaptation of its compaction level and spatiotemporal …
[HTML][HTML] SUMOylation regulates Lem2 function in centromere clustering and silencing
J Strachan, O Leidecker, C Spanos… - Journal of Cell …, 2023 - journals.biologists.com
Regulation by the small modifier SUMO is heavily dependent on spatial control of enzymes
that mediate the attachment and removal of SUMO on substrate proteins. Here, we show that …
that mediate the attachment and removal of SUMO on substrate proteins. Here, we show that …
[HTML][HTML] Disordered region of nuclear membrane protein Bqt4 recruits phosphatidic acid to the nuclear envelope to maintain its structural integrity
Y Hirano, T Sato, A Miura, Y Kubota, T Shindo… - Journal of Biological …, 2024 - Elsevier
The nuclear envelope (NE) is a permeable barrier that maintains nuclear–cytoplasmic
compartmentalization and ensures nuclear function; however, it ruptures in various …
compartmentalization and ensures nuclear function; however, it ruptures in various …
The joy of the 11th International Fission Yeast Meeting in Hiroshima (POMBE2023 Hiroshima) after a long wait due to the COVID‐19 pandemic
T Toda, K Kitamura, K Kume, M Yukawa, T Koyano… - 2023 - Wiley Online Library
Abstract The 11th International Fission Yeast Meeting took place at Astel Plaza in Hiroshima,
Japan, from May 28th to June 2nd, 2023. This highly anticipated gathering, originally …
Japan, from May 28th to June 2nd, 2023. This highly anticipated gathering, originally …
[HTML][HTML] The biological relevance of the FspTF transcription factor, homologous of Bqt4, in Fusarium sp. associated with the ambrosia beetle Xylosandrus morigerus
N Carreras-Villaseñor, LA Martínez-Rodríguez… - Frontiers in …, 2023 - frontiersin.org
Transcription factors in phytopathogenic fungi are key players due to their gene expression
regulation leading to fungal growth and pathogenicity. The KilA-N family encompasses …
regulation leading to fungal growth and pathogenicity. The KilA-N family encompasses …
[HTML][HTML] A systematic quantitative approach comprehensively defines domain-specific functional pathways linked to Schizosaccharomyces pombe heterochromatin …
A Muhammad, Z Sarkadi, T van Emden, A Mazumder… - bioRxiv, 2024 - ncbi.nlm.nih.gov
Heterochromatin plays a critical role in regulating gene expression and maintaining genome
integrity. While structural and enzymatic components have been linked to heterochromatin …
integrity. While structural and enzymatic components have been linked to heterochromatin …