Latent Autoimmune Diabetes in Adults and Metabolic Syndrome—A Mini Review

N Pan, S Yang, X Niu - Frontiers in Endocrinology, 2022 - frontiersin.org
Latent autoimmune diabetes in adults (LADA) is a heterogeneous subtype of diabetes
characterized by islet cell destruction mediated by islet autoimmunity and insulin resistance …

Maturity-onset diabetes of the young: Mutations, physiological consequences, and treatment options

H Younis, SE Ha, BG Jorgensen, A Verma… - Journal of Personalized …, 2022 - mdpi.com
Maturity-Onset Diabetes of the Young (MODY) is a rare form of diabetes which affects
between 1% and 5% of diagnosed diabetes cases. Clinical characterizations of MODY …

Identification of appropriate biochemical parameters and cut points to detect Maturity Onset Diabetes of Young (MODY) in Asian Indians in a clinic setting

R Aarthy, K Aston-Mourney, A Amutha… - Scientific Reports, 2023 - nature.com
Abstract Maturity Onset Diabetes of the Young (MODY) is a monogenic form of diabetes
which is detected by genetic testing. We looked at clinical and biochemcial variables that …

Cardio-cerebrovascular outcomes in MODY, type 1 diabetes, and type 2 diabetes: a prospective cohort study

HX Wu, TY Chu, J Iqbal, HL Jiang, L Li… - The Journal of …, 2023 - academic.oup.com
Context Cardio-cerebrovascular events are severe complications of diabetes. Objective We
aim to compare the incident risk of cardio-cerebrovascular events in maturity onset diabetes …

Integrative multi-omics approach for identifying molecular signatures and pathways and deriving and validating molecular scores for COVID-19 severity and status

D Lipman, SE Safo, T Chekouo - BMC genomics, 2023 - Springer
Background There is still more to learn about the pathobiology of COVID-19. A multi-omic
approach offers a holistic view to better understand the mechanisms of COVID-19. We used …

[HTML][HTML] Generational Diet-Induced Obesity Remodels the Omental Adipose Proteome in Female Mice

N Schuster-Little, M McCabe, K Nenninger… - Nutrients, 2024 - mdpi.com
Obesity, a complex condition that involves genetic, environmental, and behavioral factors, is
a non-infectious pandemic that affects over 650 million adults worldwide with a rapidly …

The Importance of Molecular Genetic Testing for Precision Diagnostics, Management, and Genetic Counseling in MODY Patients

LI Butnariu, DA Bizim, C Oltean, C Rusu… - International Journal of …, 2024 - mdpi.com
Maturity-onset diabetes of the young (MODY) is part of the heterogeneous group of
monogenic diabetes (MD) characterized by the non-immune dysfunction of pancreatic β …

Clinical and genetic characteristics of maturity‐onset diabetes of the young type 13: A systematic review of the literature

Y Chen, X Hu, M Zhao - Journal of Diabetes, 2024 - Wiley Online Library
Objective Maturity‐onset diabetes of the young type 13 (MODY13), a rare type of monogenic
diabetes, is often misdiagnosed as type 1 or type 2 diabetes. To improve early diagnosis …

[HTML][HTML] Assessment of pathogenicity and functional characterization of APPL1 gene mutations in diabetic patients

P Shi, Y Tian, F Xu, LN Liu, WH Wu, YZ Shi… - World Journal of …, 2024 - ncbi.nlm.nih.gov
BACKGROUND Adaptor protein, phosphotyrosine interacting with PH domain and leucine
zipper 1 (APPL1) plays a crucial role in regulating insulin signaling and glucose metabolism …

A Novel GCK Large Genomic Rearrangement in a Patient with MODY-2 Detected by Clinical Exome Sequencing

P Concolino, L Tartaglione, E De Paolis, C Carrozza… - Genes, 2022 - mdpi.com
Maturity-onset diabetes of the young (MODY) is a rare form of non-autoimmune diabetes
with an autosomal dominant inheritance. To date, 14 genes have been reported as genetic …