The biosynthesis of antibiotics and self-protection mechanisms employed by antibiotic
producers are an integral part of the growing antibiotic resistance threat. The origins of …

Enzymes are dynamic entities, and their dynamic properties are clearly linked to their
biological function. It follows that dynamics ought to play an essential role in enzyme …

Understanding protein–protein interactions (PPIs) is quite important to elucidate crucial
biological processes and even design compounds that interfere with PPIs with …

We present an updated and integrated version of our widely used protein–protein docking
and binding affinity benchmarks. The benchmarks consist of non-redundant, high-quality …

Background Dinoflagellates are known for their capacity to form harmful blooms (eg," red
tides") and as symbiotic, photosynthetic partners for corals. These unicellular eukaryotes …

Is the whole protein surface available for interaction with other proteins, or are specific sites
pre-assigned according to their biophysical and structural character? And if so, is it possible …

Interactions between macromolecules in general, and between proteins in particular, are
essential for any life process. Examples include transfer of information, inhibition or …

To the Editor: Reliable and fast computation of protein free energy is crucial for protein-
structure analysis, structure-based protein design and protein docking. Rigorous treatments …

Bifidobacteria are known as anaerobic/microaerophilic and fermentative microorganisms,
which commonly inhabit the gastrointestinal tract of various animals and insects. Analysis of …

β-Lactams are the most widely used and effective antibiotics for the treatment of infectious
diseases. Unfortunately, bacteria have developed several mechanisms to combat these …