Cellular senescence is a ubiquitous process with roles in tissue remodelling, including
wound repair and embryogenesis. However, prolonged senescence can be maladaptive …

Cellular senescence is a physiological mechanism whereby a proliferating cell undergoes a
stable cell cycle arrest upon damage or stress and elicits a secretory phenotype. This highly …

Background Peripheral vascular diseases may induce chronic ischemia and cellular injury
distal to the arterial obstruction. Cellular senescence involves proliferation arrest in …

Mitochondria are crucial bioenergetics powerhouses and biosynthetic hubs within cells,
which can generate and sequester toxic reactive oxygen species (ROS) in response to …

Inclusion body myositis (IBM) is unique across the spectrum of idiopathic inflammatory
myopathies (IIM) due to its distinct clinical presentation and refractoriness to current …

Senescence is linked to a wide range of age-associated diseases and physiological
declines. Thus, senotherapeutics are emerging to suppress the detrimental effects of …

Mitochondria are essential for eukaryotic cell activity and function, and their dysfunction is
associated with the development and progression of renal diseases. In recent years, there …

Mitochondrial dysfunction is important in the pathogenesis of various kidney diseases and
the mitochondria potentially serve as therapeutic targets necessitating further investigation …

Kidney diseases secondary to several pathogeneses affect millions of people worldwide
and have become increasingly recognized as a global public health problem. Recent …

Contrast‐induced acute kidney injury (CI‐AKI) is the third most common cause of hospital‐
acquired renal failure, with an incidence of 11%. However, the disease mechanism remains …