Midbrain dopaminergic (mDA) neuron development has been an intense area of research
during recent years. This is due in part to a growing interest in regenerative medicine and …

The midbrain dopamine (mDA) system is composed of molecularly and functionally distinct
neuron subtypes that mediate specific behaviours and are linked to various brain diseases …

Chemokines are small molecules called “chemotactic cytokines” and regulate many
processes like leukocyte trafficking, homing of immune cells, maturation, cytoskeletal …

The chemokine CXCL12/stromal cell-derived factor 1 alpha has first been described in the
immune system where it functions include chemotaxis for lymphocytes and macrophages …

The differences in size and function between primate and rodent brains, and the association
of disturbed excitatory/inhibitory balance with many neurodevelopmental disorders highlight …

WHIM syndrome is a rare combined primary immunodeficiency disease named by acronym
for the diagnostic tetrad of warts, hypogammaglobulinemia, infections, and myelokathexis …

Long-term survival rates in childhood acute lymphoblastic leukemia (ALL) are currently
above 85% due to huge improvements in treatment. However, 15-20% of children still …

Abstract “Are new neurons added in the adult mammalian brain?”“Do neural stem cells
activate following CNS diseases?”“How can we modulate their activation to promote …

Wnts are a highly conserved family of lipid-modified glycoproteins that work as morphogens
to activate several signaling pathways, leading to remodeling of the cytoskeleton and the …

Background Freezing of gait and falls represent a major burden in patients with advanced
forms of Parkinson's disease (PD). These axial motor signs are not fully alleviated by drug …