Non-covalent interactions (NCIs) are a vital component of biological bond-forming events,
and have found important applications in multiple branches of chemistry. In recent years, the …

The outcome of a glycosylation reaction critically depends on the reactivity of all reaction
partners involved: the donor glycoside (the electrophile), the activator (that generally …

The reactivity of both coupling partners—the glycosyl donor and acceptor—is decisive for
the outcome of a glycosylation reaction, in terms of both yield and stereoselectivity. Where …

Many organisms use sugars as building blocks for more complex structures in nature such
as cellulose in plants and chitin in crustaceans. To construct these large polysaccharides …

The zwitterionic Streptococcus pneumoniae serotype 1 polysaccharide (Sp1) is an important
anchor point for our immune system to act against streptococcal infections. Antibodies can …

The pre-activation based chemoselective glycosylation is a powerful strategy for
oligosaccharide synthesis with its successful application in assemblies of many complex …

The 4-OH groups of both α-and β-methyl glycosides of N-acetylglucosamine, protected with
an oxazolidinone spanning the nitrogen and O-3, and bearing benzyl or silyl protection on O …

All the possible types of the protopanaxatriol and protopanaxadiol glycosides, the major
active yet extremely heterogeneous principles of ginsengs, could be accessed by the …

A modular approach toward the synthesis of all possible trimer repeating units of the type 1
capsular polysaccharide of Streptococcus pneumonia, Sp1, is described. This zwitterionic …

This chapter describes the assembly of uronic acid containing oligosaccharides and
glycoconjugates. Two strategies are available to access these target molecules, namely a …