Pharmacological interaction between LABAs and LAMAs in the airways: optimizing synergy
L Calzetta, MG Matera, M Cazzola - European journal of pharmacology, 2015 - Elsevier
Nowadays there is solid clinical information for combining β 2-agonists and anti-muscarinic
agents, although the nature (additive or synergistic) of the net clinical result obtained by co …
agents, although the nature (additive or synergistic) of the net clinical result obtained by co …
Free radicals and antioxidants in inflammatory processes and ischemia-reperfusion injury
P Vajdovich - Veterinary Clinics of North America: Small Animal …, 2008 - Elsevier
This article discusses the current understanding of the role of free radicals and antioxidants
in inflammatory processes and in ischemia reperfusion injury. It begins by describing the …
in inflammatory processes and in ischemia reperfusion injury. It begins by describing the …
Pharmacological investigation on the anti-oxidant and anti-inflammatory activity of N-acetylcysteine in an ex vivo model of COPD exacerbation
M Cazzola, L Calzetta, F Facciolo, P Rogliani… - Respiratory …, 2017 - Springer
Background Oxidative stress is recognized to be one of predisposing factor in the
pathogenesis of COPD. The oxidant/antioxidant imbalance is significantly pronounced in …
pathogenesis of COPD. The oxidant/antioxidant imbalance is significantly pronounced in …
[HTML][HTML] Pharmacological characterization of the interaction between aclidinium bromide and formoterol fumarate on human isolated bronchi
M Cazzola, L Calzetta, CP Page, P Rogliani… - European Journal of …, 2014 - Elsevier
Long-acting muscarinic receptor antagonists (LAMAs) and long-acting β 2-adrenoceptor
agonists (LABAs) cause airway smooth muscle (ASM) relaxation via different signal …
agonists (LABAs) cause airway smooth muscle (ASM) relaxation via different signal …
Glucagon-like peptide 1 receptor: a novel pharmacological target for treating human bronchial hyperresponsiveness
P Rogliani, L Calzetta, B Capuani… - American Journal of …, 2016 - atsjournals.org
Asthma is associated with several comorbidities, such as type 2 diabetes mellitus, which
may lead to bronchial hyperresponsiveness (BHR). Because glucagon-like peptide (GLP) 1 …
may lead to bronchial hyperresponsiveness (BHR). Because glucagon-like peptide (GLP) 1 …
Pharmacological characterization of the interaction between the dual phosphodiesterase (PDE) 3/4 inhibitor RPL554 and glycopyrronium on human isolated bronchi …
L Calzetta, M Cazzola, CP Page, P Rogliani… - Pulmonary …, 2015 - Elsevier
Background The dual PDE3/4 inhibitor RPL 554 causes bronchodilation in patients with
asthma or COPD and synergistically interacts with muscarinic receptor antagonists in …
asthma or COPD and synergistically interacts with muscarinic receptor antagonists in …
Beclomethasone dipropionate and formoterol fumarate synergistically interact in hyperresponsive medium bronchi and small airways
L Calzetta, MG Matera, F Facciolo, M Cazzola… - Respiratory …, 2018 - Springer
Background Corticosteroids increase the expression of β 2-adrenoceptors (β 2-ARs) and
protect them against down-regulation. Conversely, β 2-AR agonists improve the anti …
protect them against down-regulation. Conversely, β 2-AR agonists improve the anti …
Pharmacological treatments in asthma‐affected horses: a pair‐wise and network meta‐analysis
Background Equine asthma is a disease characterised by reversible airflow obstruction,
bronchial hyper‐responsiveness and airway inflammation following exposure of susceptible …
bronchial hyper‐responsiveness and airway inflammation following exposure of susceptible …
Inflammatory and contractile profile in LPS-challenged equine isolated bronchi: Evidence for IL-6 as a potential target against AHR in equine asthma
L Calzetta, E Pistocchini, G Cito, BL Ritondo… - Pulmonary …, 2022 - Elsevier
Background Airway inflammation and airway hyperresponsiveness (AHR) are pivotal
characteristics of equine asthma. Lipopolysaccharide (LPS) may have a central role in …
characteristics of equine asthma. Lipopolysaccharide (LPS) may have a central role in …
The role of oxidative stress in an equine model of human asthma
CM Deaton - Redox Report, 2006 - Taylor & Francis
Equine recurrent airway obstruction (RAO) is a naturally occurring respiratory disease in
horses with many similarities to human asthma and, as a result, has been used as an animal …
horses with many similarities to human asthma and, as a result, has been used as an animal …