[HTML][HTML] Stroke in sickle cell disease and the promise of recent disease modifying agents

A Runge, D Brazel, Z Pakbaz - Journal of the Neurological Sciences, 2022 - Elsevier
Sickle cell disease (SCD) is an inherited hemoglobinopathy affecting approximately 100,000
individuals in the United States. Cerebrovascular disease is among the most common and …

Vascular instability and neurological morbidity in sickle cell disease: an integrative framework

H Stotesbury, JM Kawadler, PW Hales… - Frontiers in …, 2019 - frontiersin.org
It is well-established that patients with sickle cell disease (SCD) are at substantial risk of
neurological complications, including overt and silent stroke, microstructural injury, and …

Venoarterial Extracorporeal Membrane Oxygenation Therapy in Patients with Sickle Cell Disease: Case Series and Review for Intensive Care Physicians

A Grazioli, J Rabin, RP Rector, ZJ Wu… - Journal of Intensive …, 2024 - journals.sagepub.com
Sickle cell disease (SCD) is associated with substantial morbidity and early mortality in
afflicted adults. Cardiopulmonary complications that occur at increased frequency in SCD …

Abnormal Neurologic Findings in Patients With Sickle Cell Disease Without a History of Major Neurologic Events

MB Nawaiseh, AM Yassin, MQ Al-Sabbagh… - Neurology: Clinical …, 2024 - AAN Enterprises
Background and Objectives Patients with sickle cell disease (SCD) are prone to
symptomatic neurologic complications. Previous studies reported accrual of neural injury …

Successful therapeutic plasma exchange for a patient with sickle cell disease and fat embolism syndrome after a failure of a response to red cell exchange transfusion

A Alsaghir, L Alsaghir, J Alsaif, A Mobeireek - Transfusion, 2023 - Wiley Online Library
Background Fat embolism syndrome (FES) is a rare complication, which was reported
mostly with milder forms of heterozygous sickle cell disease (SCD). It may present in a …

[HTML][HTML] Fat embolism in sickle-cell disease: a case report with literature review

AM Almatar, K Kawther - Caspian Journal of Internal Medicine, 2023 - ncbi.nlm.nih.gov
Background: Sickle cell disease (SCD) is associated with an under-recognized and well-
known complication of bone marrow necrosis known as cerebral fat embolism (CFE). Case …

Bone marrow necrosis and fat embolism syndrome in sickle cell disease: A rapidly deteriorating complication.

M Barouqa, J Szymanski, R Nelson, S Jofre… - …, 2021 - search.ebscohost.com
B. Extensive bone marrow necrosis evident on histological sections taken from the autopsy
gl Marrow sections from autopsy showed ill-defined necrotic cells with amorphous …

Diverse manifestations of a sickle cell crisis

T Hashemzehi, S Bertok, MJ Figaszewska… - … Case Reports CP, 2021 - casereports.bmj.com
We describe the case of a 21-year-old man with a background of sickle cell disease (SCD)
who was on acute presentation in a sickle cell crisis required immediate intensive care …

Coma secondary to cerebral fat embolism syndrome due to sickle cell disease fully recovering following red cell exchange transfusion

N Alajeel, K Abdulmalek, A Al-Fares - BMJ Case Reports CP, 2021 - casereports.bmj.com
A 51-year-old woman known for sickle cell disease presented with 2 weeks of headache
and bilateral lower limb pain. During admission, she suffered from multiple generalised tonic …

[引用][C] Acute Chest Syndrome

AM Dessap, E Vichinsky - Sickle Cell Disease, 2021 - McGraw Hill Professional