[HTML][HTML] Pyrrolizidine alkaloids: biosynthesis, biological activities and occurrence in crop plants

S Schramm, N Köhler, W Rozhon - Molecules, 2019 - mdpi.com
Pyrrolizidine alkaloids (PAs) are heterocyclic secondary metabolites with a typical
pyrrolizidine motif predominantly produced by plants as defense chemicals against …

Overview of food safety hazards in the European dairy supply chain

ED van Asselt, HJ Van der Fels‐Klerx… - … reviews in food …, 2017 - Wiley Online Library
Monitoring of dairy products should preferably focus on the most relevant food safety
hazards in the dairy supply chain. For this purpose, the possible presence of …

Guidance on harmonised methodologies for human health, animal health and ecological risk assessment of combined exposure to multiple chemicals

EFSA Scientific Committee, SJ More, V Bampidis… - Efsa …, 2019 - Wiley Online Library
This Guidance document describes harmonised risk assessment methodologies for
combined exposure to multiple chemicals for all relevant areas within EFSA's remit, ie …

Guidance on the use of the benchmark dose approach in risk assessment

EFSA Scientific Committee, SJ More, V Bampidis… - Efsa …, 2022 - Wiley Online Library
Abstract The Scientific Committee (SC) reconfirms that the benchmark dose (BMD) approach
is a scientifically more advanced method compared to the no‐observed‐adverse‐effect …

Risks for human health related to the presence of pyrrolizidine alkaloids in honey, tea, herbal infusions and food supplements

EFSA Panel on Contaminants in the Food Chain … - EFSA …, 2017 - Wiley Online Library
EFSA was asked by the European Commission to deliver a scientific opinion on the risks for
human health related to the presence of pyrrolizidine alkaloids (PA s) in honey, tea, herbal …

Guidance Document on Scientific criteria for grouping chemicals into assessment groups for human risk assessment of combined exposure to multiple chemicals

EFSA Scientific Committee, SJ More, V Bampidis… - EFSA …, 2021 - Wiley Online Library
This guidance document provides harmonised and flexible methodologies to apply scientific
criteria and prioritisation methods for grouping chemicals into assessment groups for human …

Occurrence of pyrrolizidine alkaloids in food

PPJ Mulder, PL Sánchez, A These… - EFSA Supporting …, 2015 - Wiley Online Library
ABSTRACT A total of 1 105 samples of animal-and plant-derived products, including milk
and milk products, eggs, meat and meat products,(herbal) teas and (herbal) food …

[HTML][HTML] Metabolic toxification of 1, 2-unsaturated pyrrolizidine alkaloids causes human hepatic sinusoidal obstruction syndrome: The update

R Teschke, N Vongdala, NV Quan, TN Quy… - International Journal of …, 2021 - mdpi.com
Saturated and unsaturated pyrrolizidine alkaloids (PAs) are present in more than 6000 plant
species growing in countries all over the world. They have a typical heterocyclic structure in …

[HTML][HTML] Insight into the impact of food processing and culinary preparations on the stability and content of plant alkaloids considered as natural food contaminants

N Casado, G Casado-Hidalgo, L González-Gómez… - Applied Sciences, 2023 - mdpi.com
Pyrrolizidine alkaloids, tropane alkaloids and opium alkaloids are natural plant toxins that
have recently gained special interest in food safety due to their concerning occurrence in …

[HTML][HTML] Traces of honeybees, api-tourism and beekeeping: From past to present

E Topal, L Adamchuk, I Negri, M Kösoğlu, G Papa… - Sustainability, 2021 - mdpi.com
Throughout history, honey has been used for many different purposes and due to its
medicinal properties, has been one of the products marketed by traders. The figure of the …