Aptamers are short oligonucleotides isolated in vitro from randomized libraries that can bind
to specific molecules with high affinity, and offer a number of advantages relative to …

Nature achieves differentiation of specific and nonspecific binding in molecular interactions
through precise control of biomolecules in space and time. Artificial systems such as …

Detection of analytes by means of field-effect transistors bearing ligand-specific receptors is
fundamentally limited by the shielding created by the electrical double layer (the “Debye …

Aptamers are short single-stranded DNA or RNA oligonucleotides isolated from randomized
libraries, presenting high affinity and specificity toward targets with similar to antibodies …

Aptamers are nucleic acid molecules that mimic antibodies by folding into complex 3D
shapes that bind to specific targets. Although some aptamers exist naturally as the ligand …

The advent of SELEX (systematic evolution of ligands by exponential enrichment)
technology has shown the ability to evolve artificial ligands with affinity and specificity able to …

Over the last three decades, numerous aptamer-based biosensors have been reported. The
basis of these sensors is the selective binding of target analytes by aptamers. In the last few …

L‐lactate is a key metabolite indicative of physiological states, glycolysis pathways, and
various diseases such as sepsis, heart attack, lactate acidosis, and cancer. Detection of …

Tetracyclines are a group of important antibiotics with a common four-ring scaffold. While
most tetracyclines are currently used only in animals, their leaching into the environment …

Aptamers are single-stranded, synthetic oligonucleotides that fold into 3-dimensional
shapes capable of binding non-covalently with high affinity and specificity to a target …