In this second part of a 2-part series on the global burden of cardiovascular disease, we
review the proven, effective approaches to the prevention and treatment of cardiovascular …

Background Stroke is the third leading cause of death and the most common cause of long‐
term disability. Severe narrowing (stenosis) of the carotid artery is an important cause of …

Apolipoprotein-E (ApoE) has been implicated in Alzheimer's disease, atherosclerosis, and
other unresolvable inflammatory conditions but a common mechanism of action remains …

The management of extracranial cerebrovascular disease, including carotid endarterectomy
(CEA), carotid stenting and medical management is performed by several specialists …

Objectives To perform a systematic review of clinical practice guidelines (CPGs) and
semantic analysis of specific clinical recommendations for the management of rotator cuff …

Background and Purpose—There is no consensus on the comparative efficacy and safety of
carotid artery stenting (CAS) versus carotid endarterectomy (CEA) in patients with …

Objective To evaluate in patients with TIA and ipsilateral high-grade internal carotid artery
(ICA) stenosis whether changes in cognitive performance and cerebral hemodynamics …

Current guidelines for primary and secondary prevention of stroke in patients with carotid
atherosclerosis are based on the quantification of the degree of stenosis and symptom …

Background Treatment of individuals with asymptomatic carotid artery stenosis is still
handled controversially. Recommendations for treatment of asymptomatic carotid stenosis …

Background Stroke/death rates within 30 days of carotid endarterectomy (CEA) and carotid
artery stenting (CAS) in RCTs inform current clinical guidelines. However, the risks may …