Mechanisms and roles of podosomes and invadopodia
S Linder, P Cervero, R Eddy, J Condeelis - Nature Reviews Molecular …, 2023 - nature.com
Cell invasion into the surrounding extracellular matrix or across tissue boundaries and
endothelial barriers occurs in both physiological and pathological scenarios such as …
endothelial barriers occurs in both physiological and pathological scenarios such as …
The'ins' and'outs' of podosomes and invadopodia: characteristics, formation and function
DA Murphy, SA Courtneidge - Nature reviews Molecular cell biology, 2011 - nature.com
Podosomes and invadopodia are actin-based dynamic protrusions of the plasma membrane
of metazoan cells that represent sites of attachment to—and degradation of—the …
of metazoan cells that represent sites of attachment to—and degradation of—the …
EMT, the cytoskeleton, and cancer cell invasion
M Yilmaz, G Christofori - Cancer and Metastasis Reviews, 2009 - Springer
The metastatic process, ie the dissemination of cancer cells throughout the body to seed
secondary tumors at distant sites, requires cancer cells to leave the primary tumor and to …
secondary tumors at distant sites, requires cancer cells to leave the primary tumor and to …
Regulation of the actin cytoskeleton-plasma membrane interplay by phosphoinositides
J Saarikangas, H Zhao… - Physiological …, 2010 - journals.physiology.org
The plasma membrane and the underlying cortical actin cytoskeleton undergo continuous
dynamic interplay that is responsible for many essential aspects of cell physiology …
dynamic interplay that is responsible for many essential aspects of cell physiology …
Matrix invasion by tumour cells: a focus on MT1-MMP trafficking to invadopodia
R Poincloux, F Lizárraga… - Journal of cell science, 2009 - journals.biologists.com
When migrating away from a primary tumour, cancer cells interact with and remodel the
extracellular matrix (ECM). Matrix metalloproteinases (MMPs), and in particular the …
extracellular matrix (ECM). Matrix metalloproteinases (MMPs), and in particular the …
Cellular and molecular mechanisms of MT1-MMP-dependent cancer cell invasion
A Castro-Castro, V Marchesin… - Annual review of cell …, 2016 - annualreviews.org
Metastasis is responsible for most cancer-associated deaths. Accumulating evidence based
on 3D migration models has revealed a diversity of invasive migratory schemes reflecting …
on 3D migration models has revealed a diversity of invasive migratory schemes reflecting …
Dynamic shaping of cellular membranes by phospholipids and membrane-deforming proteins
S Suetsugu, S Kurisu, T Takenawa - Physiological reviews, 2014 - journals.physiology.org
All cellular compartments are separated from the external environment by a membrane,
which consists of a lipid bilayer. Subcellular structures, including clathrin-coated pits …
which consists of a lipid bilayer. Subcellular structures, including clathrin-coated pits …
Degrading devices: invadosomes in proteolytic cell invasion
S Linder, C Wiesner, M Himmel - Annual review of cell and …, 2011 - annualreviews.org
Podosomes and invadopodia, collectively known as invadosomes, are cell-matrix contacts
in a variety of cell types, such as monocytic cells or cancer cells, that have to cross tissue …
in a variety of cell types, such as monocytic cells or cancer cells, that have to cross tissue …
Actin machinery and mechanosensitivity in invadopodia, podosomes and focal adhesions
C Albiges-Rizo, O Destaing, B Fourcade… - Journal of cell …, 2009 - journals.biologists.com
The invasiveness of cells is correlated with the presence of dynamic actin-rich membrane
structures called invadopodia, which are membrane protrusions that are associated with …
structures called invadopodia, which are membrane protrusions that are associated with …
Cortactin regulates cofilin and N-WASp activities to control the stages of invadopodium assembly and maturation
Invadopodia are matrix-degrading membrane protrusions in invasive carcinoma cells. The
mechanisms regulating invadopodium assembly and maturation are not understood. We …
mechanisms regulating invadopodium assembly and maturation are not understood. We …