The bioisosteres of 1, 3, 4-oxadiazoles and 1, 3, 4-thiadiazoles are well-known
pharmacophores for many medicinally important drugs. Throughout the past 10 years, 1, 3, 4 …

Like the well-known sulfa drugs, Sulfonamides are ascribed to a myriad of biological
activities, including antioxidant activity. In fact, several tertiary sulfonamides, particularly N …

Abstract A new series of 1, 4-disubstituted-1, 2, 3-triazole derivatives were synthesized
through the copper-catalyzed azide-alkyne 1, 3-dipolar cycloaddition (Click chemistry) and …

Sulfonamide compounds, also known as sulfa drugs, are a significant class of synthetic
bacteriostatic antimicrobials and were the primary source of therapy against bacterial …

An iodine and base-promoted domino cyclization has been disclosed for one-pot synthesis
of 1, 3, 4-oxadiazoles via oxidative cleavage of C (sp2)-N and C (sp2)-C bonds. Herein, the …

We report robust green synthesis of novel 1, 2, 3-triazole-based sulfonamides bearing
different motifs such as fluorine under click conditions in presence of a copper-based …

A series of novel nonsymmetrical disulfides bearing 1, 3, 4-oxadiazole moiety were
designed, synthesized and evaluated for their in vitro antiproliferative activities against …

Abstract The Ag 3 PO 4-MEA catalyst was successfully prepared and proved to be an
efficient and selective catalyst of the multicomponent synthesis of a new library of 1, 4 …

In the current research, twenty-eight new 1, 3, 4-thiadiazole scaffold linked to substituted
phenacyl derivatives and disulfides were designed and synthesized, and Cell Counting Kit-8 …

A general protocol for intermolecular distal C (sp 3)-H heteroarylation of N-
fluorocarboxamides with azoles under copper catalysis has been accomplished. Notably …