Priming of the neutrophil respiratory burst: role in host defense and inflammation

J El‐Benna, M Hurtado‐Nedelec… - Immunological …, 2016 - Wiley Online Library
Neutrophils are the major circulating white blood cells in humans. They play an essential
role in host defense against pathogens. In healthy individuals, circulating neutrophils are in …

Neutrophils: between host defence, immune modulation, and tissue injury

P Kruger, M Saffarzadeh, ANR Weber, N Rieber… - PLoS …, 2015 - journals.plos.org
Neutrophils, the most abundant human immune cells, are rapidly recruited to sites of
infection, where they fulfill their life-saving antimicrobial functions. While traditionally …

[HTML][HTML] Neutrophils kill antibody-opsonized cancer cells by trogoptosis

HL Matlung, L Babes, XW Zhao, M van Houdt… - Cell reports, 2018 - cell.com
Destruction of cancer cells by therapeutic antibodies occurs, at least in part, through
antibody-dependent cellular cytotoxicity (ADCC), and this can be mediated by various Fc …

Multiple phenotypic changes define neutrophil priming

I Miralda, SM Uriarte, KR McLeish - Frontiers in cellular and infection …, 2017 - frontiersin.org
Exposure to pro-inflammatory cytokines, chemokines, mitochondrial contents, and bacterial
and viral products induces neutrophils to transition from a basal state into a primed one …

Perspectives on glycosylation and its congenital disorders

BG Ng, HH Freeze - Trends in Genetics, 2018 - cell.com
Congenital disorders of glycosylation (CDG) are a rapidly expanding group of metabolic
disorders that result from abnormal protein or lipid glycosylation. They are often difficult to …

Beta2-integrins and interacting proteins in leukocyte trafficking, immune suppression, and immunodeficiency disease

SC Fagerholm, C Guenther, M Llort Asens… - Frontiers in …, 2019 - frontiersin.org
Beta2-integrins are complex leukocyte-specific adhesion molecules that are essential for
leukocyte (eg, neutrophil, lymphocyte) trafficking, as well as for other immunological …

The molecular basis of leukocyte recruitment and its deficiencies

S Schmidt, M Moser, M Sperandio - Molecular immunology, 2013 - Elsevier
The innate immune system responds to inflammation, infection and injury by recruiting
neutrophils and other leukocytes. These cells are able to leave the intravascular …

How neutrophils kill fungi

RP Gazendam, A van de Geer, D Roos… - Immunological …, 2016 - Wiley Online Library
Neutrophils play a critical role in the prevention of invasive fungal infections. Whereas
mouse studies have demonstrated the role of various neutrophil pathogen recognition …

Two independent killing mechanisms of Candida albicans by human neutrophils: evidence from innate immunity defects

RP Gazendam, JL van Hamme… - Blood, The Journal …, 2014 - ashpublications.org
Invasive fungal infections, accompanied by high rates of mortality, represent an increasing
problem in medicine. Neutrophils are the major effector immune cells in fungal killing. Based …

The pathogenesis of giant condyloma acuminatum (Buschke-Lowenstein tumor): an overview

D Purzycka-Bohdan, RJ Nowicki, F Herms… - International Journal of …, 2022 - mdpi.com
Giant condyloma acuminatum, also known as Buschke-Lowenstein tumor (BLT), is a rare
disease of the anogenital region. BLT is considered a locally aggressive tumor of benign …