Estrogen receptor β (ERβ) is closely related to breast cancer (BC) progression. Traditional
concepts regard ERβ as a tumor suppressor. As studies show the carcinogenic effect of …

Breast cancer, a malignant tumor originating from mammary epithelial tissue, is the most
common cancer among women worldwide. Challenges facing the diagnosis and treatment …

Purpose Significant controversy exists regarding the expression patterns of estrogen
receptor beta (ERβ) in normal and diseased breast tissue. To address this issue, we have …

Glioblastoma (GBM) is the most commonly diagnosed brain tumor that exhibit high mortality
rate and chemotherapy resistance is a major clinical problem. Recent studies suggest that …

As an endocrine disruptor, tyrosine kinase inhibitor, and DNA methyltransferase inhibitor,
genistein can interfere with breast cancer development. However, as the results of …

Improving the efficacy of anticancer drugs is especially challenging. Estrogen is a sex
hormone that not only promotes the development of female secondary sexual …

The aboveground parts of Trifolium medium L.(zigzag clover), a little-known representative
of the family Fabaceae, collected during flowering in a wild stand (Sławin-Szerokie district …

Inflammatory breast cancer (IBC) is a highly metastatic breast carcinoma with high frequency
of estrogen receptor α (ERα) negativity. Here we explored the role of the second ER …

As one of the typical food-derived phytoestrogens, genistein (GEN) could bind to estrogen
receptor (ER) and was reported to be closely related to breast cancer. Our former research …

Abstract Background Glioblastomas (GBMs) are the most lethal primary brain tumors.
Estrogen receptor β (ESR2/ERβ) function as a tumor suppressor in GBM, however, ERβ …