In this paper, we reviewed the purification and characterization methods of the α-carbonic
anhydrase (CA, EC 4.2. 1.1) class. Six genetic families (α-, β-, γ-, δ-, ζ-and η-CAs) all know to …

The genome of the protozoan parasite Plasmodium falciparum, the causative agent of the
most lethal type of human malaria, contains a single gene annotated as encoding a carbonic …

Abstract Carbonic anhydrase (CA, EC 4.2. 1.1) inhibitors (CAIs) started to be used in the
treatment of peptic ulcers in the 1970s, and for more than two decades, a group led by Ioan …

Ischemia of brain areas is a global health problem, causing death or long-term disability.
Current pharmacological options have limited impact on ischemic damages. Recently, a …

6-Substituted sulfocoumarins bearing the carboxamido, trimethylammonium as well as the
cyano and methoxy moieties with interesting inhibitory activity/selectivity against the tumor …

Coumarins behave as inhibitors of the metalloenzyme carbonic anhydrase (CA, EC 4.2. 1.1)
with a mechanism of inhibition distinct from other classes of inhibitors. A series of 7 …

A series of dithiocarbamates (DTCs) was investigated for the inhibition of the β-class
carbonic anhydrase (CAs, EC 4.2. 1.1) from the fungal parasite Malassezia globosa, MgCA …

A series of carbamate derivatives were synthesized and their carbonic anhydrase I and II
isoenzymes and acetylcholinesterase enzyme (AChE) inhibitory effects were investigated …

A series of novel 2-aminobenzothiazole derivatives bearing sulfonamide at position 6 was
designed, synthesized and investigated as inhibitors of four isoforms of the metalloenzyme …

A series of N 1-substituted aromatic sulfonamides was obtained by applying a selective
sulfonamide nitration synthetic strategy leading to Ar-SO 2 NHNO 2 derivatives which were …