Human life expectancy has increased over the past few centuries, and the incidence of
dementia in the older population is also projected to continue to rise. Neurodegenerative …

Recent years have seen a profound resurgence of activity with nonhuman primates (NHPs)
to model human brain disorders. From marmosets to macaques, the study of NHP species …

Concerns about poor animal to human translation have come increasingly to the fore, in
particular with regards to cognitive improvements in rodent models, which have failed to …

The investigation of neurobiological and neuropathological changes that affect synaptic
integrity and function with aging is key to understanding why the aging brain is vulnerable to …

Executive control is a higher‐level cognitive function that involves a range of different
processes that are involved in the planning, coordination, execution, and inhibition of …

Researchers and veterinarians often use hematology and clinical chemistry to evaluate
animal health. These biomarkers are relatively easy to obtain, and understanding how they …

The amygdala is an important hub for regulating emotions and is involved in the
pathophysiology of many mental diseases, such as depression and anxiety. Meanwhile, the …

Age-related osteoarthritis (OA) is a degenerative joint disease characterized by pathological
changes in nearly every intra-and peri-articular tissue that contributes to disability in older …

Across the lifespan, the performance in problem-solving tasks varies strongly, owing to age-
related variation in cognitive abilities as well as the motivation to engage in a task. Non …

Emerging evidence indicates that antibiotic-induced dysbiosis can play an etiological role in
the pathogenesis of neuropsychiatric disorders. However, most of this evidence comes from …