Soil viral diversity, ecology and climate change

JK Jansson, R Wu - Nature Reviews Microbiology, 2023 - nature.com
Soil viruses are highly abundant and have important roles in the regulation of host dynamics
and soil ecology. Climate change is resulting in unprecedented changes to soil ecosystems …

Engineered bacteriophage therapeutics: rationale, challenges and future

M Łobocka, K Dąbrowska, A Górski - BioDrugs, 2021 - Springer
The current problems with increasing bacterial resistance to antibacterial therapies, resulting
in a growing frequency of incurable bacterial infections, necessitates the acceleration of …

A roadmap for genome-based phage taxonomy

D Turner, AM Kropinski, EM Adriaenssens - Viruses, 2021 - mdpi.com
Bacteriophage (phage) taxonomy has been in flux since its inception over four decades ago.
Genome sequencing has put pressure on the classification system and recent years have …

IMG/VR v3: an integrated ecological and evolutionary framework for interrogating genomes of uncultivated viruses

S Roux, D Páez-Espino, IMA Chen… - Nucleic acids …, 2021 - academic.oup.com
Viruses are integral components of all ecosystems and microbiomes on Earth. Through
pervasive infections of their cellular hosts, viruses can reshape microbial community …

[HTML][HTML] The gut virome database reveals age-dependent patterns of virome diversity in the human gut

AC Gregory, O Zablocki, AA Zayed, A Howell… - Cell host & …, 2020 - cell.com
The gut microbiome profoundly affects human health and disease, and their infecting viruses
are likely as important, but often missed because of reference database limitations. Here, we …

Systematic exploration of Escherichia coli phage–host interactions with the BASEL phage collection

E Maffei, A Shaidullina, M Burkolter, Y Heyer… - PLoS …, 2021 - journals.plos.org
Bacteriophages, the viruses infecting bacteria, hold great potential for the treatment of
multidrug-resistant bacterial infections and other applications due to their unparalleled …

Update of the list of qualified presumption of safety (QPS) recommended microorganisms intentionally added to food or feed as notified to EFSA

EFSA Panel on Biological Hazards (BIOHAZ)… - EFSA …, 2023 - Wiley Online Library
The qualified presumption of safety (QPS) provides a generic pre‐assessment of the safety
of microorganisms intended for use in the food or feed chains, to support the work of EFSA's …

Viral biogeography of the mammalian gut and parenchymal organs

AN Shkoporov, SR Stockdale, A Lavelle… - Nature …, 2022 - nature.com
The mammalian virome has been linked to health and disease but our understanding of how
it is structured along the longitudinal axis of the mammalian gastrointestinal tract (GIT) and …

Hi-C metagenome sequencing reveals soil phage–host interactions

R Wu, MR Davison, WC Nelson, ML Smith… - Nature …, 2023 - nature.com
Bacteriophages are abundant in soils. However, the majority are uncharacterized, and their
hosts are unknown. Here, we apply high-throughput chromosome conformation capture (Hi …

Major tail proteins of bacteriophages of the order Caudovirales

M Zinke, GF Schröder, A Lange - Journal of Biological Chemistry, 2022 - ASBMB
Technological advances in cryo-EM in recent years have given rise to detailed atomic
structures of bacteriophage tail tubes—a class of filamentous protein assemblies that could …