Executive summary The number of older people, including those living with dementia, is
rising, as younger age mortality declines. However, the age-specific incidence of dementia …

Cognitive abilities are important predictors of educational and occupational performance,
socioeconomic attainment, health, and longevity. Declines in cognitive abilities are linked to …

A major unanswered question in the dementia field is whether cognitively unimpaired
individuals who harbor both Alzheimer's disease neuropathological hallmarks (that is …

Alzheimer's disease (AD) is the most common cause of dementia worldwide, but the
molecular and cellular mechanisms underlying cognitive impairment remain poorly …

Background Risk of dementia after stroke is a major concern for patients and carers.
Reliable data for risk of dementia, particularly after transient ischaemic attack or minor …

This systematic review aims to summarize cognitive reserve (CR) evaluation approaches
and to examine the role of seven selected modifiable lifestyle factors (diet, smoking, alcohol …

Background: Dementia is a devastating neurologic condition that is common in older adults.
We previously reviewed the epidemiological evidence examining the hypothesis that long …

Objective To test the hypothesis that distinct subtypes of Alzheimer disease (AD) exist and
underlie the heterogeneity within AD, we conducted a systematic review and meta-analysis …

As the population ages, the number of people with dementia is expected to increase in the
coming decades, with consequences at the societal and individual levels. In this narrative …

Little is still known about the neuroanatomical substrates related to changes in specific
cognitive abilities in the course of healthy aging, and the existing evidence is predominantly …