Conclusions Dinitrogen tetroxide is a long-stablished reagent that has been widely applied
in many organic reactions as a nitrating, nitrosating and oxidisting agent. The diversity this …

Hantzsch reaction, leading to the synthesis of 1, 4‐dihydropyridines (1, 4‐DHPs) with
momentous biological activities and pharmacological properties is a well‐known MCR. In …

Synthesis of various N-nitroso compounds from secondary amines is reported using tert-
butyl nitrite (TBN) under solvent free conditions. Broad substrate scope, metal and acid free …

tert-Butyl nitrite (TBN) is an important metal-free reagent that is widely applied in various
organic transformations. Besides its traditional applications in nitrosation and diazotization …

A simple, green and cost-effective protocol was achieved for the solvent free synthesis of 1,
4-dihydropyridines catalyzed by AlCl3· 6H2O as a mild and effective catalyst at 60° C in high …

Nitrophenols can be obtained in moderate to high yields via nitrosation-oxidation of phenols
with silica sulfuric acid, NaNO2 and wet SiO2 at room temperature. In situ generation of …

An iodide-catalyzed process to synthesize N-nitrosamines has been developed using TBHP
as the oxidant. The mild catalytic system succeeded in cleaving the carbon–nitrogen bond in …

Secondary nitroalkanes underwent oxygen-mediated nitro–nitrite isomerization, serving as
versatile N-nitrosating agents under aerobic conditions. To capitalize on the newly …

Nitrophenols can be obtained in high yields via NITROSATION-OXIDATION of phenols by 3-
methyl-1-sulfonic acid imidazolium chloride f [Msim] Clg as a new BRONSTED ACIDIC …

N-Nitroso compounds have been listed as one of the cohorts of concern as per ICH M7. In
recent years, the regulatory focus has shifted from common nitrosamines to nitroso …