Antimicrobial peptides (AMPs) are a class of short, usually positively charged polypeptides
that exist in humans, animals, and plants. Considering the increasing number of drug …

The perennial leguminous herb Clitoria ternatea (butterfly pea) has attracted significant
interest based on its agricultural and medical applications, which range from use as a fodder …

In the last century, small-molecule natural products were the main inspiration for most drug
discovery programs based either on high-throughput screening (HTS) or rational design …

Toxins have evolved to target regions of membrane ion channels that underlie ligand
binding, gating, or ion permeation, and have thus served as invaluable tools for probing …

CyBase was originally developed as a database for backbone-cyclized proteins, providing
search and display capabilities for sequence, structure and function data. Cyclic proteins are …

Engineered antibodies and their fragments are invaluable tools for a vast range of
biotechnological and pharmaceutical applications. However, they are facing increasing …

Cyclotides are small disulfide-rich peptides that are characterized by a head-to-tail cyclized
peptide backbone and a knotted arrangement of three conserved disulfide bonds. They are …

Protease inhibitors (PIs) are regulatory proteins found in numerous animal tissues and
fluids, plants, and microorganisms that reduce and inhibit the exacerbated and uncontrolled …

This review on all spider venom components known by the end of 2010 bases on 1618
records for venom compounds from 174 spider species (= 0.41% of all known species) …

Knottins, or inhibitor cystine knots (ICKs), are ultra-stable miniproteins with multiple
applications in drug design and medical imaging. These widespread and functionally …