Although synovitis is the pathological hallmark of rheumatoid arthritis (RA), many extra-
articular manifestations (EMs) and comorbidities likely occur due to the complex, chronic …

Acute kidney injury (AKI) is a growing problem with untoward economic and medical
consequences. Anticancer drug toxicity remains an important and increasing cause of AKI …

Biotherapeutics are increasingly becoming the mainstay in the treatment of a variety of
human conditions, particularly in oncology and hematology. The production of therapeutic …

Anti-tumour necrosis factor (TNF)-α agents have been increasingly used to treat patients
affected by inflammatory bowel disease and dermatological and rheumatologic inflammatory …

Drug-induced autoimmune disease was initially described decades ago, with reports of
vasculitis and a lupus-like syndrome in patients taking hydralazine, procainamide, and …

Rheumatoid arthritis is associated with reduced kidney function, possibly due to chronic
inflammation or the use of nephrotoxic therapies. However, little is known about the effects of …

Drugs are associated frequently with the development of various types of acute and chronic
kidney diseases. Nephrotoxicity is associated most commonly with injury in the …

The aim of the study was to evaluate the influence of metabolic syndrome (MetS) on
achieving minimal disease activity (MDA) in psoriatic arthritis (PsA) patients treated with anti …

Background Biological agents that contain substances affecting the immune system are
increasingly being used to treat chronic inflammatory systemic diseases. Aside from the …

Chimeric fusion proteins, produced by genetic engineering, are currently made up of effector
peptides, for example, a ligand-binding portion of a cytokine or growth factor, extracellular …