In patients with cirrhosis and chronic liver disease, acute-on-chronic liver failure is emerging
as a major cause of mortality. These guidelines indicate the preferred approach to the …

Since the 1960s, methicillin-resistant Staphylococcus aureus (MRSA) has emerged,
disseminated globally and become a leading cause of bacterial infections in both health …

High throughput DNA sequencing methodology (next generation sequencing; NGS) has
rapidly evolved over the past 15 years and new methods are continually being …

Nanopore DNA strand sequencing has emerged as a competitive, portable technology.
Reads exceeding 150 kilobases have been achieved, as have in-field detection and …

The revolution of genome sequencing is continuing after the successful second-generation
sequencing (SGS) technology. The third-generation sequencing (TGS) technology, led by …

Clinical microbiology has long relied on growing bacteria in culture to determine
antimicrobial susceptibility profiles, but the use of whole-genome sequencing for antibiotic …

Infections in Patients with Cirrhosis Patients with cirrhosis are at increased risk for serious
infections, including spontaneous bacterial peritonitis, multidrug-resistant infection, and …

Background Bloodstream infections remain one of the major challenges in intensive care
units, leading to sepsis or even septic shock in many cases. Due to the lack of timely …

Realizing the democratic promise of nanopore sequencing requires the development of new
bioinformatics approaches to deal with its specific error characteristics. Here we present …

EFSA and EMA have jointly reviewed measures taken in the EU to reduce the need for and
use of antimicrobials in food‐producing animals, and the resultant impacts on antimicrobial …