Carbapenem resistance is a major and an on-going public health problem globally. It occurs
mainly among Gram-negative pathogens such as Klebsiella pneumoniae, Pseudomonas …

Klebsiella pneumoniae carbapenemases (KPCs) were originally identified in the USA in
1996. Since then, these versatile β-lactamases have spread internationally among Gram …

Klebsiella pneumoniae is an important opportunistic pathogen that commonly causes
nosocomial infections and contributes to substantial morbidity and mortality. We sought to …

The spread of Enterobacteriaceae, primarily Klebsiella pneumoniae, producing KPC, VIM,
IMP, and NDM carbapenemases, is causing an unprecedented public health crisis …

Multilocus sequence typing reveals that many bacterial species have a clonal structure and
that some clones are widespread. This underlying phylogeny was not revealed by pulsed …

From early this decade, Enterobacteriaceae that produce Klebsiella pneumoniae
carbapenemases (KPC) were reported in the USA and subsequently worldwide. These KPC …

Bacteria producing Klebsiella pneumoniae carbapenemases (KPCs) are rapidly emerging
as a cause of multidrug-resistant infections worldwide. Bacterial isolates harbouring these …

Bacterial resistance to antibiotics has become a major source of concern for public health.
Enterobacteriaceae are among the most common human pathogens, causing community …

Objectives To develop a single multiplex real-time PCR assay to detect six different genetic
types of carbapenemases already identified in Enterobacteriaceae (KPC, GES, NDM, IMP …

Klebsiella pneumoniae isolates that produce carbapenemases (KPCs) are rapidly
disseminating worldwide. To determine their genetic background, we investigated 16 bla …