Synthetic DNA is of increasing demand across many sectors of research and commercial
activities. Engineering biology, therapy, data storage and nanotechnology are set for rapid …

Microarrays are one of the hottest areas in biological research today. Microarrays have been
mostly applied to nucleic acid analysis, specifically to the assessment of which genes are …

Advances in new micro-and nanotechnologies are accelerating the identification and
evaluation of drug candidates, and the development of new delivery technologies that are …

The possibility of wavelength-selective cleavage of seven photolabile caging groups from
different families has been studied. Amine-, thiol-, and carboxylic-terminated organosilanes …

Miniaturized, spatially addressable microchips of peptides and peptidomimetics are
powerful tools for high-throughput biomedical and pharmaceutical research and the …

In situ synthesis of oligonucleotide microarrays - Gao - 2004 - Biopolymers - Wiley Online Library
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Devices, systems, and methods for an oligonucleotide syn thesis engine. In on embodiment,
the invention involves a micro? uidic device including: an oligonucleotide synthesis subunit …

Oligonucleotide microarrays or oDNA chips are effective decoding and analytical tools for
genomic sequences and are useful for a broad range of applications. Therefore, it is …

Large DNA constructs of arbitrary sequences can currently be assembled with relative ease
by joining short synthetic oligodeoxynucleotides (oligonucleotides). The ability to mass …

We demonstrate a new method for making oligonucleotide microarrays by synthesis in situ.
The method uses conventional DNA synthesis chemistry with an electrochemical deblocking …