C3‐substituted indoles and carbazoles react with α‐aryl‐α‐diazoesters under palladium
catalysis to form α‐(N‐indolyl)‐α‐arylesters and α‐(N‐carbazolyl)‐α‐arylesters. The …

Abstract β-Lactam rings containing compounds are a group of antibiotics of unparalleled
importance in chemotherapy. Considerable effort has been reported in the development of …

In this chapter, a comprehensive overview of the most significant and interesting
contributions published from 2000 until now, concerning the preparation of novel β-lactam …

Reaction of the β-lactam-based oxazolidinone 5 with N-sulfonylimines provides the exo and
endo azapenams 8 in 22–54% yield. The reactivity of 2H-azirines as 1, 3-dipolarophiles …

C4-phenylthio β-lactams are a new family of antibacterial agents that have activity against
two phylogenetically distant bacteria–Mycobacterium tuberculosis (Mtb) and Moraxella …

Antimicrobial resistance represents a global threat to healthcare. The ability to adequately
treat infectious diseases is increasingly under siege due to the emergence of drug-resistant …

In this paper, we report reversible capture and release of aromatic amines by
diphenylpropanetrione (DPPT). Addition of aromatic amines to the central carbonyl group …

New types of monocyclic ${\beta} $-lactams constitute an important class of compounds due
to their unique structures and natures. Here, the design and synthesis of new 4-alkylthio …

The prevalence of drug resistance in both clinical and community settings as a consequence
of alterations of biosynthetic pathways, enzymes or cell wall architecture is a persistent …

The double-edged sword of antibiotic use in the fight against disease has saved countless
lives at the cost of an escalation in pathogenic bacteria with increased resistance to multiple …