Many physiologic differences between children and adults can result in age‐related
differences in pharmacokinetics. Understanding the effects of age on bioavailability, volume …

Management of high blood pressure in children and adolescent... : Journal of Hypertension
Management of high blood pressure in children and adolescents: recommendations of the …

Highlights•Pharmacokinetics data are too limited to support an age-related effect on
enalapril.•Moderate strong evidence supports enalapril's efficacy in older hypertensive …

Despite widespread use to treat childhood hypertension, enalapril has never been studied
systematically to determine effectiveness, dose response, and safety in a pediatric …

La hipertensión en niños y adolescentes ha ido ganando terreno en la medicina
cardiovascular, gracias a los avances producidos en distintas áreas de la investigación …

The RAS (renin–angiotensin system) is classically involved in BP (blood pressure)
regulation and water–electrolyte balance, and in the central nervous system it has been …

BACKGROUND: The number of antihypertensive agents on the market has increased
dramatically over the past 20 years. Many of these agents are used to treat children and …

Background Information regarding efficacy of the angiotensin II receptor blocker, telmisartan,
for treatment of proteinuria in dogs is limited. Objective To evaluate the antiproteinuric …

Introduction Off‐label drug use in the paediatric population is common, and the lack of high‐
quality efficacy studies poses patients at risk for failing pharmacotherapy. Next to efficacy …

The incidence of pediatric hypertension (HTN) is increasing, mainly due to an increase in
primary (essential) HTN, or PH. There are only a limited number of studies assessing the …