Normal haemostasis depends on an intricate balance between mechanisms of bleeding and
mechanisms of thrombosis, and this balance can be altered after traumatic brain injury (TBI) …

Intracerebral hemorrhage (ICH) refers to primary, spontaneous, nontraumatic bleeding
occurring in the brain parenchyma. ICH accounts for 10% to 20% of all cerebrovascular …

The risk of bleeding in the setting of anticoagulant therapy continues to be re-evaluated
following the introduction of a new generation of direct oral anticoagulants (DOACs) …

Traumatic brain injury (TBI) is a growing global problem, which is responsible for a
substantial burden of disability and death, and which generates substantial healthcare costs …

A unique coagulopathy often manifests following traumatic brain injury, leading the clinician
down a difficult decision path on appropriate prophylaxis and therapy. Conventional …

Traumatic brain injury (TBI) is a worldwide public health concern due to increasing mortality,
affecting around 10 million patients per year. A wide variety of clinical presentations are a …

Spontaneous intracerebral hemorrhage (ICH) is a medical emergency with potentially
devastating morbidity and mortality. After ischemic stroke, ICH represents the second most …

Although there is controversy about the absolute need for a reversal agent for the new direct
oral anticoagulants (DOACs), the absence of such an agent is a barrier to more widespread …

Introduction To describe the population admitted in an emergency department of a teaching
hospital for severe bleeding associated with direct oral anticoagulants (DOAC). Method …

The vitamin K antagonists (VKAs) have been the standard (and only) oral anticoagulants
used for the long-term treatment or prevention of venous thromboembolism or stroke in …