[HTML][HTML] Atopic Dermatitis in Children and Adults: Diagnosis and Treatment
A Wollenberg, T Werfel, J Ring, H Ott… - Deutsches Ärzteblatt …, 2023 - ncbi.nlm.nih.gov
Background Atopic dermatitis is a common, chronically recurring inflammatory skin disease.
It gives rise to a high disease burden and is of major importance in social medicine. Methods …
It gives rise to a high disease burden and is of major importance in social medicine. Methods …
[HTML][HTML] The landscape of GWAS validation; systematic review identifying 309 validated non-coding variants across 130 human diseases
AJ Alsheikh, S Wollenhaupt, EA King, J Reeb… - BMC medical …, 2022 - Springer
Background The remarkable growth of genome-wide association studies (GWAS) has
created a critical need to experimentally validate the disease-associated variants, 90% of …
created a critical need to experimentally validate the disease-associated variants, 90% of …
SNPs in sites for DNA methylation, transcription factor binding, and miRNA targets leading to allele-specific gene expression and contributing to complex disease risk …
Introduction: The complex genetic diversity among human populations results from an
assortment of factors acting at various sequential levels, including mutations, population …
assortment of factors acting at various sequential levels, including mutations, population …
[HTML][HTML] DNA double-strand break response and repair gene polymorphisms may influence therapy results and prognosis in head and neck cancer patients
D Butkiewicz, M Krześniak, A Gdowicz-Kłosok… - Cancers, 2023 - mdpi.com
Simple Summary Head and neck cancer (HNC) is characterized by radio-and
chemoresistance contributing to treatment failure and poor prognosis. There is evidence that …
chemoresistance contributing to treatment failure and poor prognosis. There is evidence that …
A polymorphism in the TH2 locus control region is associated with changes in DNA methylation and gene expression
Background Genomewide association and epigenetic studies found a region within the RAD
50 gene on chromosome 5q31 to be associated with total serum IgE levels and asthma. In …
50 gene on chromosome 5q31 to be associated with total serum IgE levels and asthma. In …
Latest developments in allergic rhinitis in Allergy for clinicians and researchers
CL Ng, DY Wang - Allergy, 2015 - Wiley Online Library
Research efforts in allergic rhinitis have always been intense. Over the past 3 years,
numerous breakthroughs in basic science and clinical research have been made …
numerous breakthroughs in basic science and clinical research have been made …
[HTML][HTML] Critical role of epigenetic modification in the pathogenesis of atopic dermatitis
C Chen, J Zeng, J Lu - Indian Journal of Dermatology, Venereology and …, 2023 - ijdvl.com
Atopic dermatitis is a chronic inflammatory skin disease characterised by recurrent eczema-
like lesions and severe pruritus, along with drying and decrustation of skin. Current research …
like lesions and severe pruritus, along with drying and decrustation of skin. Current research …
Allele-specific quantitative proteomics unravels molecular mechanisms modulated by cis-regulatory PPARG locus variation
H Lee, K Qian, C von Toerne, L Hoerburger… - Nucleic acids …, 2017 - academic.oup.com
Genome-wide association studies identified numerous disease risk loci. Delineating
molecular mechanisms influenced by cis-regulatory variants is essential to understand gene …
molecular mechanisms influenced by cis-regulatory variants is essential to understand gene …
Genetics of atopic eczema: An update
E Rodríguez, S Weidinger - Der Hautarzt, 2015 - Springer
Das atopische Ekzem ist eine typische multifaktorielle Erkrankung, bei der Umwelt-und
Lebensstilfaktoren eine individuell vererbte Disposition in die Manifestation führen. Die …
Lebensstilfaktoren eine individuell vererbte Disposition in die Manifestation führen. Die …
Genetics and aetiology of atopic dermatitis
E Rodriguez, S Weidinger - Harper's Textbook of Pediatric …, 2019 - Wiley Online Library
Atopic dermatitis or eczema represents a typical multifactorial disease in that there is an
individual hereditary predisposition that is triggered by environmental and lifestyle factors …
individual hereditary predisposition that is triggered by environmental and lifestyle factors …