Neurobiology of glycine transporters: From molecules to behavior

BL Marques, OC Oliveira-Lima, GA Carvalho… - Neuroscience & …, 2020 - Elsevier
Abstract Glycine transporters (GlyTs) are Na+/Cl−-dependent neurotransmitter transporters,
responsible for l-glycine uptake into the central nervous system. GlyTs are members of the …

Postoperative analgesic effect of hydromorphone in patients undergoing single-port video-assisted thoracoscopic surgery: a randomized controlled trial

Y Bai, K Sun, X Xing, F Zhang, N Sun, Y Gao… - Journal of pain …, 2019 - Taylor & Francis
Objective: To study the general efficacy of hydromorphone as a systemic analgesic in
postoperative pain management following single-port video-assisted thoracoscopic surgery …

Role of VVZ-149, a novel analgesic molecule, in the affective component of pain: Results from an exploratory proof-of-concept study of postoperative pain following …

I Song, S Cho, SS Nedeljkovic, SR Lee, C Lee… - Pain …, 2021 - academic.oup.com
Objective VVZ-149 is a small molecule that both inhibits the glycine transporter type 2 and
the serotonin receptor 5 hydroxytryptamine 2 A. In a randomized, parallel-group, and double …

MS binding assays for Glycine transporter 2 (GlyT2) employing Org25543 as reporter ligand

TM Ackermann, L Allmendinger, G Höfner… - …, 2021 - Wiley Online Library
This study describes the first binding assay for glycine transporter 2 (GlyT2) following the
concept of MS Binding Assays. The selective GlyT2 inhibitor Org25543 was employed as a …

[引用][C] VVZ-149

N Shaparin - 2019