Sepsis: mechanisms of bacterial injury to the patient

H Minasyan - Scandinavian journal of trauma, resuscitation and …, 2019 - Springer
In bacteremia the majority of bacterial species are killed by oxidation on the surface of
erythrocytes and digested by local phagocytes in the liver and the spleen. Sepsis-causing …

Sepsis and septic shock: Pathogenesis and treatment perspectives

H Minasyan - Journal of critical care, 2017 - Elsevier
The majority of bacteremias do not develop to sepsis: bacteria are cleared from the
bloodstream. Oxygen released from erythrocytes and humoral immunity kill bacteria in the …

Sepsis, cytokine storms, and immunopathology: the divide between neonates and adults

KG Greenfield, VP Badovinac, TS Griffith… - …, 2021 - journals.aai.org
Sepsis can result from a variety of pathogens, originating from a range of sources. A vast
range of presenting symptoms is included in the catch-all term of “bacteremia,” making …

Hospital-acquired infections at an oncological intensive care cancer unit: differences between solid and hematological cancer patients

P Cornejo-Juárez, D Vilar-Compte… - BMC infectious …, 2016 - Springer
Background Cancer patients have a higher risk of severe sepsis in comparison with non-
cancer patients, with an increased risk for hospital-acquired infections (HAI), particularly with …

Advances in patents related to intrapocket technology for the management of periodontitis

SK Yadav, G Khan, B Mishra - Recent patents on drug delivery …, 2015 - ingentaconnect.com
Increased prevalence of oral diseases such as gingivitis, periodontitis and dental caries has
become major health issue worldwide. Such growing incidence of periodontitis has directly …

How to approach and treat VAP in ICU patients

B Borgatta, J Rello - BMC infectious diseases, 2014 - Springer
Background Ventilator-associated pneumonia (VAP) is one of the most frequent clinical
problems in ICU with an elevated morbidity and costs associated with it, in addition to …

How to measure the impacts of antibiotic resistance and antibiotic development on empiric therapy: new composite indices

JS Hughes, A Hurford, RL Finley, DM Patrick, J Wu… - BMJ open, 2016 - bmjopen.bmj.com
Objectives We aimed to construct widely useable summary measures of the net impact of
antibiotic resistance on empiric therapy. Summary measures are needed to communicate …

Bioactive doped metals: high synergism in the bactericidal activity of chlorhexidine@ silver towards wound pathogenic bacteria

R Ben-Knaz, R Pedahzur, D Avnir - Rsc Advances, 2013 - pubs.rsc.org
The entrapment of chlorhexidine (CH) within metallic silver (CH@ Ag) results in a composite
material bearing powerful synergetic bactericidal action towards two opportunistic wound …

Antibiotic therapy in patients with septic shock

J Textoris, S Wiramus, C Martin… - European Journal of …, 2011 - journals.lww.com
The management of a patient with severe sepsis is first to diagnose the infection, to collect
samples immediately after diagnosis and to initiate promptly broad-spectrum antibiotic …

Agreement on the prescription of antimicrobial drugs

E Casaroto, AR Marra, TZS Camargo… - BMC infectious …, 2015 - Springer
Background There is universal awareness of the difficulties faced by doctors when
prescribing antimicrobials. Methods Over a six-month period patients hospitalized in the ICU …