Nanoencapsulation of essential oils and their bioactive constituents: A novel strategy to control mycotoxin contamination in food system

AK Chaudhari, VK Singh, S Das, NK Dubey - Food and Chemical …, 2021 - Elsevier
Spoilage of food by mycotoxigenic fungi poses a serious risk to food security throughout the
world. In view of the negative effects of synthetic preservatives, essential oils (EOs) and their …

[HTML][HTML] Black cumin (Nigella sativa) and its active constituent, thymoquinone: an overview on the analgesic and anti-inflammatory effects

B Amin, H Hosseinzadeh - Planta medica, 2016 - thieme-connect.com
For many centuries, seeds of Nigella sativa (black cumin), a dicotyledon of the
Ranunculaceae family, have been used as a seasoning spice and food additive in the …

Encapsulation of phenolic compounds within nano/microemulsion systems: A review

F Garavand, M Jalai-Jivan, E Assadpour, SM Jafari - Food Chemistry, 2021 - Elsevier
Phenolic compounds (phenolics) have received great attention in the food, pharmaceutical
and nutraceutical industries due to their health-promoting attributes. However, their …

[HTML][HTML] Thymoquinone (2-Isopropyl-5-methyl-1, 4-benzoquinone) as a chemopreventive/anticancer agent: Chemistry and biological effects

A Ahmad, RK Mishra, A Vyawahare, A Kumar… - Saudi Pharmaceutical …, 2019 - Elsevier
Cancer remains the topmost disorder of the mankind and number of cases is unceasingly
growing at unprecedented rates. Although the synthetic anti-cancer compounds still hold the …

Brain targeting efficiency of antimigrain drug loaded mucoadhesive intranasal nanoemulsion

EM Abdou, SM Kandil, HMF El Miniawy - International journal of …, 2017 - Elsevier
Zolmitriptan (ZT) is a well-tolerated drug in migraine treatment suffering from low
bioavailability due to low amount of the drug that reaches the brain after oral and nasal …

Oral bioavailability enhancement and hepatoprotective effects of thymoquinone by self-nanoemulsifying drug delivery system

MA Kalam, M Raish, A Ahmed, KM Alkharfy… - Materials Science and …, 2017 - Elsevier
Thymoquinone (TQ) is a poorly water soluble bioactive compound which shows poor oral
bioavailability upon oral administration. Due to poor aqueous solubility and bioavailability of …

Neuropharmacological potential and delivery prospects of thymoquinone for neurological disorders

M Jakaria, DY Cho, M Ezazul Haque… - Oxidative medicine …, 2018 - Wiley Online Library
Thymoquinone (TQ) is an active ingredient isolated from Nigella sativa and has various
pharmacological activities, such as protection against oxidative stress, inflammation, and …

[HTML][HTML] Hepatoprotective effects of bioflavonoid luteolin using self-nanoemulsifying drug delivery system

F Shakeel, MM Alamer, P Alam, A Alshetaili, N Haq… - Molecules, 2021 - mdpi.com
Luteolin (LUT) is a natural pharmaceutical compound that is weakly water soluble and has
low bioavailability when taken orally. As a result, the goal of this research was to create self …

Mechanistic perspectives on cancer chemoprevention/chemotherapeutic effects of thymoquinone

J Kundu, KS Chun, OI Aruoma, JK Kundu - … Research/Fundamental and …, 2014 - Elsevier
The bioactive natural products (plant secondary metabolites) are widely known to possess
therapeutic value for the prevention and treatment of various chronic diseases including …

Molecular modeling study of structures, Hirschfield surface, NBO, AIM, RDG, IGM and 1HNMR of thymoquinone/hydroxypropyl-β-cyclodextrin inclusion complex from …

K Rayene, D Imane, B Abdelaziz, N Leila… - Journal of Molecular …, 2022 - Elsevier
In this work, the thymoquinone (TQ)/hydroxypropyl-β-cyclodextrin (HPβ-CD) inclusion
complex has been investigated employing quantum mechanical calculations in gas phase …