This study describes the occurrence of renal failure among 1353 newly diagnosed cases of
multiple myeloma. Renal function was evaluated by serum creatinine concentration in 1353 …

The assembly of a multiple sequence alignment (MSA) has become one of the most
common tasks when dealing with sequence analysis. Unfortunately, the wide range of …

DALI is a popular resource for comparing protein structures. The software is based on
distance‐matrix alignment. The associated web server provides tools to navigate, integrate …

Comparative protein structure modeling predicts the three‐dimensional structure of a given
protein sequence (target) based primarily on its alignment to one or more proteins of known …

Zinc fingers are small protein domains in which zinc plays a structural role contributing to the
stability of the domain. Zinc fingers are structurally diverse and are present among proteins …

▪ Abstract We can now assign about two thirds of the sequences from completed genomes to
as few as 1400 domain families for which structures are known and thus more ancient …

This paper presents Tcoffee@ igs, a new server provided to the community by Hewlet
Packard computers and the Centre National de la Recherche Scientifique. This server is a …

The dynamics of proteins in aqueous solution has been investigated through a massive
approach based on “state of the art” molecular dynamics simulations performed for all …

Conspectus The zinc-dependent histone deacetylases (HDACs 1–11) belong to the
arginase-deacetylase superfamily of proteins, members of which share a common α/β fold …

Prions are fatal neurodegenerative transmissible agents causing several incurable illnesses
in humans and animals. Prion diseases are caused by the structural conversion of the …