Shared and divergent principles of synaptic transmission between cortical excitatory neurons in rodent and human brain

CPJ de Kock, D Feldmeyer - Frontiers in Synaptic Neuroscience, 2023 - frontiersin.org
Information transfer between principal neurons in neocortex occurs through (glutamatergic)
synaptic transmission. In this focussed review, we provide a detailed overview on the …

Parvalbumin interneuron cell-to-network plasticity: mechanisms and therapeutic avenues

MD Hadler, H Alle, JRP Geiger - Trends in Pharmacological Sciences, 2024 - cell.com
Alzheimer's disease (AD) and schizophrenia (SCZ) represent two major neuropathological
conditions with a high disease burden. Despite their distinct etiologies, patients suffering …

Of mice and men: topologically complex dendrites assemble uniquely human networks

L Kanari, Y Shi, A Arnaudon, N Barros-Zulaica… - bioRxiv, 2023 - biorxiv.org
The organizational principles that distinguish the human brain from other species have been
a long-standing enigma in neuroscience. Focusing on the uniquely evolved cortical layers 2 …

FitzHugh–Nagumo Model in Neutral Delay Differential Equation Representation

MA Elfouly, MA Sohaly, ME Fares - 2024 - researchsquare.com
Action potentials are a crucial physiological event for body regulation and sensory
information detection. This study represented a modification of FitzHugh-Nagumo model as …

Genomic, molecular, and cellular divergence of the human brain

R Nehme, O Pietiläinen, LE Barrett - Trends in Neurosciences, 2024 - cell.com
While many core biological processes are conserved across species, the human brain has
evolved with unique capacities. Current understanding of the neurobiological mechanisms …