Polymeric nanoparticles, nanospheres and nanocapsules, for cutaneous applications

SS Guterres, MP Alves, AR Pohlmann - Drug target insights, 2007 - journals.sagepub.com
This review presents an overview about pharmaceutical and cosmetic topical products
containing polymeric nanoparticles (nanospheres and nanocapsules), reporting the main …

In vitro skin models as a tool in optimization of drug formulation

GE Flaten, Z Palac, A Engesland… - European journal of …, 2015 - Elsevier
Abstract (Trans) dermal drug therapy is gaining increasing importance in the modern drug
development. To fully utilize the potential of this route, it is important to optimize the delivery …

In vitro permeation of gold nanoparticles through rat skin and rat intestine: effect of particle size

G Sonavane, K Tomoda, A Sano, H Ohshima… - Colloids and Surfaces B …, 2008 - Elsevier
Purpose of the present work was to study in vitro permeation of gold nanoparticles (NPs)
through isolated rat skin and intestine. Another objective was to see the effect of particle size …

The tape stripping procedure–evaluation of some critical parameters

J Lademann, U Jacobi, C Surber, HJ Weigmann… - European Journal of …, 2009 - Elsevier
Tape stripping is a simple and efficient method for the assessment of quality and efficacy of
cosmetical and dermatological formulations. After topical application and penetration of …

Topical delivery of lipophilic drugs from o/w Pickering emulsions

J Frelichowska, MA Bolzinger, J Pelletier… - International journal of …, 2009 - Elsevier
Surfactant-free emulsions stabilized by solid particles (Pickering emulsions) have been
evaluated in the terms of skin absorption of lipophilic drugs. The behavior of three …

Advanced progress of microencapsulation technologies: In vivo and in vitro models for studying oral and transdermal drug deliveries

PL Lam, R Gambari - Journal of Controlled Release, 2014 - Elsevier
This review provides an overall discussion of microencapsulation systems for both oral and
transdermal drug deliveries. Clinically, many drugs, especially proteins and peptides, are …

Transdermal delivery of mixnoxidil with block copolymer nanoparticles

J Shim, HS Kang, WS Park, SH Han, J Kim… - Journal of Controlled …, 2004 - Elsevier
We evaluated the effect of hydrodynamic size of self-assembled nanoparticles on skin
penetration of minoxidil in vitro and in vivo. Self-assembled 40-and 130-nm nanoparticles …

Nanoparticulate delivery systems for antiviral drugs

D Lembo, R Cavalli - Antiviral Chemistry and Chemotherapy, 2010 - journals.sagepub.com
Nanomedicine opens new therapeutic avenues for attacking viral diseases and for
improving treatment success rates. Nanoparticulate-based systems might change the …

Lipid nanoparticles for prolonged topical delivery: an in vitro and in vivo investigation

C Puglia, P Blasi, L Rizza, A Schoubben… - International journal of …, 2008 - Elsevier
Dermal therapy is still a challenge due to the difficulties in controlling the active
pharmaceutical ingredient (API) fate within the skin. Recently, lipid nanoparticles have …

Biocompatible stabilizers in the preparation of PLGA nanoparticles: a factorial design study

J Vandervoort, A Ludwig - International journal of pharmaceutics, 2002 - Elsevier
Poly (lactic-co-glycolic-acid) nanoparticles are often produced using the w/o/w emulsification
solvent evaporation method. In most cases poly (vinyl alcohol)(PVA) is used as stabilizer of …