Nanoporous gold: A review and potentials in biotechnological and biomedical applications

S Xiao, S Wang, X Wang, P Xu - Nano Select, 2021 - Wiley Online Library
Nanoporous gold (NPG) is one of the representatives of emerging materials that combine
the advantages of nano, porous, and metallic materials. In addition to the general …

Applications of nanoporous gold in therapy, drug delivery, and diagnostics

P Sondhi, D Lingden, JK Bhattarai, AV Demchenko… - Metals, 2022 - mdpi.com
Nanoporous gold (np-Au) has promising applications in therapeutic delivery. The promises
arise from its high surface area-to-volume ratio, ease of tuning shape and size, ability to be …

Nanoporous gold as a neural interface coating: effects of topography, surface chemistry, and feature size

CAR Chapman, H Chen, M Stamou… - … applied materials & …, 2015 - ACS Publications
Designing neural interfaces that maintain close physical coupling of neurons to an electrode
surface remains a major challenge for both implantable and in vitro neural recording …

Effect of nanoporous gold thin film morphology on electrochemical DNA sensing

P Daggumati, Z Matharu, E Seker - Analytical chemistry, 2015 - ACS Publications
Advances in materials science and chemistry have led to the development of a wide range
of nanostructured materials for building novel electrochemical biosensors. A systematic …

Nanoporous-gold-based electrode morphology libraries for investigating structure–property relationships in nucleic acid based electrochemical biosensors

Z Matharu, P Daggumati, L Wang… - … applied materials & …, 2017 - ACS Publications
Nanoporous gold (np-Au) electrode coatings significantly enhance the performance of
electrochemical nucleic acid biosensors because of their three-dimensional nanoscale …

SEEDING to enable sensitive electrochemical detection of biomarkers in undiluted biological samples

J Sabaté del Río, HK Woo, J Park, HK Ha… - Advanced …, 2022 - Wiley Online Library
Electrochemical biosensors have shown great potential for simple, fast, and cost‐effective
point‐of‐care diagnostic tools. However, direct analysis of complex biological fluids such as …

Cell biology is different in small volumes: endogenous signals shape phenotype of primary hepatocytes cultured in microfluidic channels

A Haque, P Gheibi, Y Gao, E Foster, KJ Son, J You… - Scientific reports, 2016 - nature.com
The approaches for maintaining hepatocytes in vitro are aimed at recapitulating aspects of
the native liver microenvironment through the use of co-cultures, surface coatings and 3D …

Interplay of effective surface area, mass transport, and electrochemical features in nanoporous nucleic acid sensors

J Veselinovic, S AlMashtoub, S Nagella… - Analytical …, 2020 - ACS Publications
Electrochemical biosensors transduce biochemical events (eg, DNA hybridization) to
electrical signals and can be readily interfaced with electronic instrumentation for portability …

Anomalous trends in nucleic acid-based electrochemical biosensors with nanoporous gold electrodes

J Veselinovic, S Almashtoub, E Seker - Analytical chemistry, 2019 - ACS Publications
Molecular diagnostics have significantly advanced the early detection of diseases, where
electrochemical sensing of biomarkers has shown considerable promise. For a nucleic acid …

Primary cortical cell tri-culture-based screening of neuroinflammatory response in toll-like receptor activation

N Goshi, H Kim, E Seker - Biomedicines, 2022 - mdpi.com
The activation of toll-like receptors (TLRs) in the central nervous system (CNS) can lead to
neuroinflammation and contribute to many neurological disorders, including autoimmune …