Hypoxia signaling in human health and diseases: implications and prospects for therapeutics

Z Luo, M Tian, G Yang, Q Tan, Y Chen, G Li… - Signal transduction and …, 2022 - nature.com
Molecular oxygen (O2) is essential for most biological reactions in mammalian cells. When
the intracellular oxygen content decreases, it is called hypoxia. The process of hypoxia is …

Helicobacter pylori infection, its laboratory diagnosis, and antimicrobial resistance: a perspective of clinical relevance

S Ansari, Y Yamaoka - Clinical microbiology reviews, 2022 - Am Soc Microbiol
Despite the recent decrease in overall prevalence of Helicobacter pylori infection, morbidity
and mortality rates associated with gastric cancer remain high. The antimicrobial resistance …

[PDF][PDF] 中国胃癌筛查与早诊早治指南(2022, 北京)

赫捷, 陈万青, 李兆申, 李霓, 任建松, 田金徽… - 中国 …, 2022 - xadxyylib.yuntsg.com
胃癌是我国常见的恶性肿瘤之一, 严重威胁我国居民生命健康. 胃癌高风险人群接受筛查和早诊
早治能够有效降低胃癌的发病率和死亡率. 制定符合中国国情的胃癌筛查与早诊早治指南 …

[HTML][HTML] Management of epithelial precancerous conditions and lesions in the stomach (maps II): European Society of gastrointestinal endoscopy (ESGE), European …

P Pimentel-Nunes, D Libânio, R Marcos-Pinto… - …, 2019 - thieme-connect.com
Patients with chronic atrophic gastritis or intestinal metaplasia (IM) are at risk for gastric
adenocarcinoma. This underscores the importance of diagnosis and risk stratification for …

Mucosal microbiota of intestinal polyps reveals putative biomarkers of colorectal cancer

M Mangifesta, L Mancabelli, C Milani, F Gaiani… - Scientific reports, 2018 - nature.com
The human intestine retains a complex microbial ecosystem, which performs crucial
functions that impact on host health. Several studies have indicated that intestinal dysbiosis …

The Colombian chemoprevention trial: 20-year follow-up of a cohort of patients with gastric precancerous lesions

MB Piazuelo, LE Bravo, RM Mera, MC Camargo… - Gastroenterology, 2021 - Elsevier
Background & Aims Helicobacter pylori eradication and endoscopic surveillance of gastric
precancerous lesions are strategies to reduce gastric cancer (GC) risk. To our knowledge …

Gastritis staging in the endoscopic follow-up for the secondary prevention of gastric cancer: a 5-year prospective study of 1755 patients

M Rugge, A Meggio, C Pravadelli, M Barbareschi… - Gut, 2019 - gut.bmj.com
Objective Operative link on gastritis assessment (OLGA) staging for gastritis ranks the risk for
gastric cancer (GC) in progressive stages (0–IV). This prospective study aimed at quantifying …

Study of Microbiomes in Aseptically Collected Samples of Human Breast Tissue Using Needle Biopsy and the Potential Role of in situ Tissue Microbiomes for …

S Meng, B Chen, J Yang, J Wang, D Zhu… - Frontiers in …, 2018 - frontiersin.org
Mounting evidence suggests that changes in microbiome are linked to development of
cancer and its aggressiveness. Microbiome profiles in human breast tissue previously …

AGA technical review on gastric intestinal metaplasia—natural history and clinical outcomes

AJ Gawron, SC Shah, O Altayar, P Davitkov… - …, 2020 - gastrojournal.org
Gastric cancer is the third leading cause of cancer-related mortality and the fifth most
common cancer globally. An estimated 1 million new cases and 750,000 related deaths are …

Gastritis: The clinico-pathological spectrum

M Rugge, E Savarino, M Sbaraglia, L Bricca… - Digestive and Liver …, 2021 - Elsevier
The inflammatory spectrum of gastric diseases includes different clinico-pathological
entities, the etiology of which was recently established in the international Kyoto …