Oxidative stress and sperm function: A systematic review on evaluation and management

S Dutta, A Majzoub, A Agarwal - Arab journal of urology, 2019 - Taylor & Francis
Objective: To review and present the most distinct concepts on the association of reactive
oxygen species (ROS) with male reproduction. Methods: The Preferred Reporting Items for …

Oxidative stress and male infertility: current knowledge of pathophysiology and role of antioxidant therapy in disease management

E Barati, H Nikzad, M Karimian - Cellular and Molecular Life Sciences, 2020 - Springer
Infertility is a global health problem involving about 15% of couples. Approximately half of
the infertility cases are related to male factors. The oxidative stress, which refers to an …

Sperm DNA fragmentation testing: Summary evidence and clinical practice recommendations

SC Esteves, A Zini, RM Coward, DP Evenson… - Andrologia, 2021 - Wiley Online Library
We herein summarise the evidence concerning the impact of sperm DNA fragmentation in
various clinical infertility scenarios and the advances on sperm DNA fragmentation tests …

[HTML][HTML] Clinical utility of sperm DNA fragmentation testing: practice recommendations based on clinical scenarios

A Agarwal, A Majzoub, SC Esteves, E Ko… - Translational …, 2016 - ncbi.nlm.nih.gov
Sperm DNA fragmentation (SDF) has been generally acknowledged as a valuable tool for
male fertility evaluation. While its detrimental implications on sperm function were …

Effect of oxidative stress on male reproduction

A Agarwal, G Virk, C Ong… - The world journal of …, 2014 - synapse.koreamed.org
Infertility affects approximately 15% of couples trying to conceive, and a male factor
contributes to roughly half of these cases. Oxidative stress (OS) has been identified as one …

Molecular changes induced by oxidative stress that impair human sperm motility

K Nowicka-Bauer, B Nixon - Antioxidants, 2020 - mdpi.com
A state of oxidative stress (OS) and the presence of reactive oxygen species (ROS) in the
male reproductive tract are strongly correlated with infertility. While physiological levels of …

Varicocele and male infertility

CFS Jensen, P Østergren, JM Dupree, DA Ohl… - Nature Reviews …, 2017 - nature.com
The link between varicoceles and male infertility has been a matter of debate for more than
half a century. Varicocele is considered the most common correctable cause of male …

Intracytoplasmic sperm injection for male infertility and consequences for offspring

SC Esteves, M Roque, G Bedoschi, T Haahr… - Nature Reviews …, 2018 - nature.com
Intracytoplasmic sperm injection (ICSI) has become the most commonly used method of
fertilization in assisted reproductive technology. The primary reasons for its popularity stem …

Causes, effects and molecular mechanisms of testicular heat stress

D Durairajanayagam, A Agarwal, C Ong - Reproductive biomedicine online, 2015 - Elsevier
The process of spermatogenesis is temperature-dependent and occurs optimally at
temperatures slightly lower than that of the body. Adequate thermoregulation is imperative to …

Sperm DNA damage caused by oxidative stress: modifiable clinical, lifestyle and nutritional factors in male infertility

C Wright, S Milne, H Leeson - Reproductive biomedicine online, 2014 - Elsevier
DNA fragmentation is an important factor in the aetiology of male infertility. However, it is still
underevaluated and its inclusion in routine semen analysis is debated. DNA fragmentation …