Analytical device miniaturization for the detection of circulating biomarkers
Diverse (sub) cellular materials are secreted by cells into the systemic circulation at different
stages of disease progression. These circulating biomarkers include whole cells, such as …
stages of disease progression. These circulating biomarkers include whole cells, such as …
Programmable Nanostructures Based on Framework-DNA for Applications in Biosensing
B Liu, F Wang, J Chao - Sensors, 2023 - mdpi.com
DNA has been actively utilized as bricks to construct exquisite nanostructures due to their
unparalleled programmability. Particularly, nanostructures based on framework DNA (F …
unparalleled programmability. Particularly, nanostructures based on framework DNA (F …
Cascading CRISPR/Cas and Nanozyme for Enhanced Organic Photoelectrochemical Transistor Detection with Triple Signal Amplification
L Zhang, L Hou, HH Cai, B Sun, DM Han… - Analytical …, 2024 - ACS Publications
Innovative signal amplification and transduction play pivotal roles in bioanalysis. Herein,
cascading CRISPR/Cas and the nanozyme are integrated with electronic amplification in an …
cascading CRISPR/Cas and the nanozyme are integrated with electronic amplification in an …
Detection of SARS-CoV-2 RNA with a plasmonic chiral biosensor
Z Yu, L Pan, X Ma, T Li, F Wang, D Yang, M Li… - Biosensors and …, 2023 - Elsevier
The detection of SARS-CoV-2 infection is crucial for effective prevention and surveillance of
COVID-19. In this study, we report the development of a novel detection assay named …
COVID-19. In this study, we report the development of a novel detection assay named …
Bidirectional linkage of DNA barcodes for the multiplexed mapping of higher-order protein interactions in cells
Y Liu, NR Sundah, NRY Ho, WX Shen, Y Xu… - Nature Biomedical …, 2024 - nature.com
Capturing the full complexity of the diverse hierarchical interactions in the protein
interactome is challenging. Here we report a DNA-barcoding method for the multiplexed …
interactome is challenging. Here we report a DNA-barcoding method for the multiplexed …
Magnetic augmentation through multi-gradient coupling enables direct and programmable profiling of circulating biomarkers
Y Chen, L Zhang, X Wu, X Sun, NR Sundah… - Nature …, 2024 - nature.com
Conventional magnetic biosensing technologies have reduced analytical capacity for
magnetic field dimensionality and require extensive sample processing. To address these …
magnetic field dimensionality and require extensive sample processing. To address these …
CoVSense: Ultrasensitive Nucleocapsid Antigen Immunosensor for Rapid Clinical Detection of Wildtype and Variant SARS‐CoV‐2
The widespread accessibility of commercial/clinically‐viable electrochemical diagnostic
systems for rapid quantification of viral proteins demands translational/preclinical …
systems for rapid quantification of viral proteins demands translational/preclinical …
Protein-nucleic acid hybrid nanostructures for molecular diagnostic applications
NR Sundah, Y Seah, A Natalia, X Chen, P Cen, Y Liu… - Nano Research, 2024 - Springer
Molecular diagnostic technologies empower new clinical opportunities in precision
medicine. However, existing approaches face limitations with respect to performance …
medicine. However, existing approaches face limitations with respect to performance …
Multiplexed RNA profiling by regenerative catalysis enables blood-based subtyping of brain tumors
Current technologies to subtype glioblastoma (GBM), the most lethal brain tumor, require
highly invasive brain biopsies. Here, we develop a dedicated analytical platform to achieve …
highly invasive brain biopsies. Here, we develop a dedicated analytical platform to achieve …
DNA‐Mediated Control of Protein Function in Semi‐Synthetic Systems
DM Snider, S Pandit, ML Coffin, SB Ebrahimi… - …, 2022 - Wiley Online Library
The development of strategies for controlling protein function in a precise and predictable
manner has the potential to revolutionize catalysis, diagnostics, and medicine. In this regard …
manner has the potential to revolutionize catalysis, diagnostics, and medicine. In this regard …