Omega-6 fatty acids and inflammation

JK Innes, PC Calder - Prostaglandins, Leukotrienes and Essential Fatty …, 2018 - Elsevier
Inflammation is a normal process that is part of host defence and tissue healing. However,
excessive or unresolved inflammation can lead to uncontrolled tissue damage, pathology …

Omega-3 fatty acids and inflammatory processes: from molecules to man

PC Calder - Biochemical Society Transactions, 2017 - portlandpress.com
Inappropriate, excessive or uncontrolled inflammation contributes to a range of human
diseases. Inflammation involves a multitude of cell types, chemical mediators and …

Marine omega-3 fatty acids and inflammatory processes: Effects, mechanisms and clinical relevance

PC Calder - Biochimica et Biophysica Acta (BBA)-Molecular and …, 2015 - Elsevier
Inflammation is a condition which contributes to a range of human diseases. It involves a
multitude of cell types, chemical mediators, and interactions. Eicosapentaenoic acid (EPA) …

Very long-chain n-3 fatty acids and human health: fact, fiction and the future

PC Calder - Proceedings of the Nutrition Society, 2018 - cambridge.org
EPA and DHA appear to be the most important n-3 fatty acids, but roles for n-3
docosapentaenoic acid are now also emerging. Intakes of EPA and DHA are usually low …

Metabolism and functional effects of plant-derived omega-3 fatty acids in humans

EJ Baker, EA Miles, GC Burdge, P Yaqoob… - Progress in lipid …, 2016 - Elsevier
Alpha-linolenic acid (ALA) is an essential fatty acid and the substrate for the synthesis of
longer-chain, more unsaturated ω-3 fatty acids, eicosapentaenoic acid (EPA) …

Omega‐3 polyunsaturated fatty acids and inflammatory processes: nutrition or pharmacology?

PC Calder - British journal of clinical pharmacology, 2013 - Wiley Online Library
Eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) are n‐3 fatty acids found in
oily fish and fish oil supplements. These fatty acids are able to inhibit partly a number of …

Dietary factors and low-grade inflammation in relation to overweight and obesity

PC Calder, N Ahluwalia, F Brouns, T Buetler… - British Journal of …, 2011 - cambridge.org
Low-grade inflammation is a characteristic of the obese state, and adipose tissue releases
many inflammatory mediators. The source of these mediators within adipose tissue is not …

[HTML][HTML] Mechanisms of action of (n-3) fatty acids

PC Calder - The Journal of nutrition, 2012 - Elsevier
Abstract (n-3) PUFA are a family of biologically active fatty acids. The simplest member of
this family, a-linolenic acid, can be converted to the more biologically active very long-chain …

Long-chain polyunsaturated fatty acids (LCPUFAs) and the developing immune system: a narrative review

EA Miles, CE Childs, PC Calder - Nutrients, 2021 - mdpi.com
The immune system is complex: it involves many cell types and numerous chemical
mediators. An immature immune response increases susceptibility to infection, whilst …

Docosahexaenoic acid

PC Calder - Annals of Nutrition and Metabolism, 2016 - karger.com
Docosahexaenoic acid (DHA) is a long-chain, highly unsaturated omega-3 (n-3) fatty acid. It
has a structure that gives it unique physical and functional properties. DHA is metabolically …