Reawakening the intrinsic cardiac regenerative potential: molecular strategies to boost dedifferentiation and proliferation of endogenous cardiomyocytes

C Bongiovanni, F Sacchi, S Da Pra… - Frontiers in …, 2021 - frontiersin.org
Despite considerable efforts carried out to develop stem/progenitor cell-based technologies
aiming at replacing and restoring the cardiac tissue following severe damages, thus far no …

A cross-species analysis of systemic mediators of repair and complex tissue regeneration

J Losner, K Courtemanche, JL Whited - NPJ Regenerative Medicine, 2021 - nature.com
Regeneration is an elegant and complex process informed by both local and long-range
signals. Many current studies on regeneration are largely limited to investigations of local …

Heart development and regeneration—a multi‐organ effort

A Filosa, S Sawamiphak - The FEBS journal, 2023 - Wiley Online Library
Development of the heart, from early morphogenesis to functional maturation, as well as
maintenance of its homeostasis are tasks requiring collaborative efforts of cardiac tissue and …

Downregulation of Hotair or LSD1 Impaired Heart Regeneration in the Neonatal Mouse

Q Fei, M Qiu, G Fan, B Zhang, Q Wang… - DNA and Cell …, 2021 - liebertpub.com
Previous studies have shown that lysine-specific demethylase 1 (LSD1) could regulate cell
cycle progression through demethylation. The 3′ domain of HOX transcript antisense RNA …

Glucocorticoid Receptor Antagonism and Cardiomyocyte Regeneration following Myocardial Infarction: A Systematic Review

Y Sethi, I Padda, SA Sebastian, A Malhi, G Malhi… - Current Problems in …, 2023 - Elsevier
Abstract Background and Objectives Myocardial regeneration has been a topic of interest in
literature and research in recent years. An evolving approach reported is glucocorticoid (GC) …