Gonadotropin-inhibitory hormone (GnIH) and its control of central and peripheral reproductive function

K Tsutsui, GE Bentley, G Bedecarrats, T Osugi… - Frontiers in …, 2010 - Elsevier
Identification of novel neurohormones that regulate the reproductive axis is essential for the
progress of neuroendocrinology. The decapeptide gonadotropin-releasing hormone (GnRH) …

Gonadotropin-inhibitory hormone (GnIH): discovery, progress and prospect

K Tsutsui, T Ubuka, GE Bentley, LJ Kriegsfeld - General and comparative …, 2012 - Elsevier
A hypothalamic neuropeptide, gonadotropin-releasing hormone (GnRH), is the primary
factor regulating gonadotropin secretion. An inhibitory hypothalamic neuropeptide for …

Potent action of RFamide-related peptide-3 on pituitary gonadotropes indicative of a hypophysiotropic role in the negative regulation of gonadotropin secretion

IJ Clarke, IP Sari, Y Qi, JT Smith, HC Parkington… - …, 2008 - academic.oup.com
We identified a gene in the ovine hypothalamus encoding for RFamide-related peptide-3
(RFRP-3), and tested the hypothesis that this system produces a hypophysiotropic hormone …

[PDF][PDF] Hypophysiotropic role of RFamide-related peptide-3 in the inhibition of LH secretion in female rats

M Murakami, T Matsuzaki, T Iwasa, T Yasui… - Journal of …, 2008 - Citeseer
Abstract Gonadotropin-inhibitory hormone (GnIH), a newly discovered hypothalamic
RFamide peptide, inhibits reproductive activity by decreasing gonadotropin synthesis and …

The effects of light pollution on biological rhythms of birds: an integrated, mechanistic perspective

DM Dominoni - Journal of Ornithology, 2015 - Springer
Light pollution is considered a threat for biodiversity given the extent to which it can affect a
vast number of behavioral and physiological processes in several species. This comes as …

A new key neurohormone controlling reproduction, gonadotropin-inhibitory hormone (GnIH): Biosynthesis, mode of action and functional significance

K Tsutsui - Progress in neurobiology, 2009 - Elsevier
Identification of novel neurohormones that play important roles in the regulation of pituitary
function is essential for the progress of neurobiology. The decapeptide gonadotropin …

Discovery and evolutionary history of gonadotrophin‐inhibitory hormone and kisspeptin: new key neuropeptides controlling reproduction

K Tsutsui, GE Bentley, LJ Kriegsfeld… - Journal of …, 2010 - Wiley Online Library
Gonadotrophin‐releasing hormone (GnRH) is the primary hypothalamic factor responsible
for the control of gonadotrophin secretion in vertebrates. However, within the last decade …

Alterations in RFamide-related peptide expression are coordinated with the preovulatory luteinizing hormone surge

EM Gibson, SA Humber, S Jain, WP Williams III… - …, 2008 - academic.oup.com
The preovulatory LH surge is triggered when the circadian pacemaker, the bilateral
suprachiasmatic nucleus (SCN), stimulates the GnRH system in the presence of high …

Gonadotropin-inhibitory hormone and its receptor in the avian reproductive system

GE Bentley, T Ubuka, NL McGuire… - General and …, 2008 - Elsevier
Many hormones that are classified as neuropeptides are synthesized in vertebrate gonads
in addition to the brain. Receptors for these hormones are also expressed in gonadal tissue; …

Melatonin and male reproduction

C Li, X Zhou - Clinica Chimica Acta, 2015 - Elsevier
Melatonin is a neurohormone secreted by the pineal gland whose concentrations in the
body are regulated by both the dark–light and seasonal cycles. The reproductive function of …