Objective: The aim of this study was to conduct a systematic review and meta-analysis to
clarify the diagnostic accuracy of intraoperative breast margin assessment (IMA) techniques …

Inadequate margins continue to occur frequently in patients who undergo surgical resection
of a tumor, suggesting that current intraoperative methods are not sufficiently reliable in …

Background Re-operation for positive resection margins following breast-conserving surgery
occurs frequently (average= 20–25%), is cost-inefficient, and leads to physical and …

Probing the mechanical properties of tissue on the microscale could aid in the identification
of diseased tissues that are inadequately detected using palpation or current clinical …

Rapid intraoperative assessment of breast excision specimens is clinically important
because up to 40% of patients undergoing breast-conserving cancer surgery require …

Background and purpose Breast cancer is one of the most widely recognized tumors..
Diagnosis made in the early stage of disease may imporve outcomes. The discovery of …

Background Multiple recent reports have documented significant variability of reoperation
rates after initial lumpectomy for breast cancer. To address this issue, a multidisciplinary …

Background A multicenter, prospective, blinded study was performed to test the feasibility of
using a handheld optical imaging probe for the intraoperative assessment of final surgical …

Breast-conserving surgery (BCS) is a commonly utilized treatment for early stage breast
cancers but has relatively high reexcision rates due to post-surgical identification of positive …

Background Breast cancer surgeons struggle with differentiating healthy tissue from cancer
at the resection margin during surgery. We report on the feasibility of using diffuse …