The Japanese clinical practice guidelines for management of sepsis and septic shock 2020 (J-SSCG 2020)

M Egi, H Ogura, T Yatabe, K Atagi, S Inoue, T Iba… - Journal of intensive …, 2021 - Springer
Abstract The Japanese Clinical Practice Guidelines for Management of Sepsis and Septic
Shock 2020 (J-SSCG 2020), a Japanese-specific set of clinical practice guidelines for sepsis …

The diagnostic accuracy of procalcitonin and C‐reactive protein for sepsis: A systematic review and meta‐analysis

M Tan, Y Lu, H Jiang, L Zhang - Journal of cellular biochemistry, 2019 - Wiley Online Library
Background The objective of this study was to systematically evaluate the clinical value of
procalcitonin and C‐reactive protein in the diagnosis of adult patients with sepsis. Method …

Biomarkers in pneumonia—beyond procalcitonin

M Karakioulaki, D Stolz - International journal of molecular sciences, 2019 - mdpi.com
Pneumonia is the leading infectious cause of mortality worldwide and one of the most
common lower respiratory tract infections that is contributing significantly to the burden of …

Diagnostic value of procalcitonin and presepsin for sepsis in critically ill adult patients: a systematic review and meta-analysis

Y Kondo, Y Umemura, K Hayashida, Y Hara… - Journal of Intensive …, 2019 - Springer
Background Early and accurate diagnosis of sepsis is challenging. Although procalcitonin
and presepsin have been identified as potential biomarkers to differentiate between sepsis …

Two new neutrophil subsets define a discriminating sepsis signature

A Meghraoui-Kheddar, BG Chousterman… - American Journal of …, 2022 - atsjournals.org
Rationale: Sepsis is the leading cause of death in adult ICUs. At present, sepsis diagnosis
relies on nonspecific clinical features. It could transform clinical care to have immune-cell …

Current evidence and limitation of biomarkers for detecting sepsis and systemic infection

SK Hung, HM Lan, ST Han, CC Wu, KF Chen - Biomedicines, 2020 - mdpi.com
Sepsis was recently redefined as a life-threatening disease involving organ dysfunction
caused by a dysregulated host response to infection. Biomarkers play an important role in …

Mass spectrometry for the discovery of biomarkers of sepsis

KR Ludwig, AB Hummon - Molecular BioSystems, 2017 - pubs.rsc.org
Sepsis is a serious medical condition that occurs in 30% of patients in intensive care units
(ICUs). Early detection of sepsis is key to prevent its progression to severe sepsis and septic …

A novel combination of biomarkers to herald the onset of sepsis prior to the manifestation of symptoms

HH Dolin, TJ Papadimos, S Stepkowski, X Chen… - Shock, 2018 - journals.lww.com
Abstract Sepsis, which kills over 200,000 patients and costs over $20 billion in the United
States alone, presents a constant but preventable challenge in the healthcare system …

[HTML][HTML] Early lactate/albumin and procalcitonin/albumin ratios as predictors of 28-day mortality in ICU-admitted sepsis patients: A retrospective cohort study

F Li, Z Ye, J Zhu, S Gu, S Peng, Y Fang… - … Medical Journal of …, 2023 - ncbi.nlm.nih.gov
Background Lactate/albumin (LA/ALB) and procalcitonin/albumin (PCT/ALB) ratios have
been implicated in predicting mortality in sepsis patients. However, their prognostic value …

Early blood biomarkers to improve sepsis/bacteremia diagnostics in pediatric emergency settings

E Tamelytė, G Vaičekauskienė, A Dagys, T Lapinskas… - Medicina, 2019 - mdpi.com
Background: Sepsis is the leading cause of death in children worldwide. Early recognition
and treatment are essential for preventing progression to lethal outcomes. CRP and …