Krüppel-like factor 4 (KLF4) is an evolutionarily conserved zinc finger-containing
transcription factor that regulates diverse cellular processes such as cell growth …

Desmosomes are intercellular junctions, which preserve tissue integrity during homeostatic
and stress conditions. These functions rely on their unique structural properties, which …

Desmosomes are intercellular junctions that mediate cell–cell adhesion and anchor the
intermediate filament network to the plasma membrane, providing mechanical resilience to …

The traditional model of intercellular junctions protecting the ocular surface epithelia has
recently been expanded to include an additional glycan shield that lines apical membranes …

The structural and functional integrity of the ocular surface, a continuous epithelial structure
comprised of the cornea, the conjunctiva, and the ductal surface of the lacrimal as well as …

Krüppel-like factor 4 (KLF4) is a transcription factor highly conserved in evolution. It is
particularly well known for its role in inducing pluripotent stem cells. In addition, KLF4 plays …

Blood‐tumor barrier (BTB) constitutes an efficient organization of tight junctions which
significantly reduce permeability for chemotherapy drugs. Krüppel‐like factor 4 (KLF4), a …

Conjunctival goblet cells (CGCs) are specialized cells that produce and secrete soluble
mucins to the tear film that bathes the ocular surface. CGC numbers and functions are …

By providing a physical and immunological barrier, the ocular surface serves the important
function of protecting the vision apparatus. The barrier function keeps the cornea relatively …

The ocular surface—a continuous epithelial surface with regional specializations including
the surface and glandular epithelia of the cornea, conjunctiva, and lacrimal and meibomian …